FDA Needs More Data on Tebipenem HBr for Complicated UTI
In the CRL, the FDA stated that the application could not be approved in its present form and that an additional clinical trial would be required.
Diagnosis & Disease Information
Travelers’ Diarrhea Significantly Increases Urinary Tract Infection Risk
Researchers assessed whether there is an association between urinary tract infection incidence and international travel.
Efficacy of Standard Piperacillin Dosing in Children on Continuous Kidney Replacement Therapy
Researchers assessed the pharmacokinetics of piperacillin to determine whether standard dosing provides adequate exposure in critically ill children receiving continuous kidney replacement therapy.
Cefepime-Taniborbactam Bests Meropenem in Complicated UTI Trial
The phase 3 CERTAIN-1 study compared the efficacy and safety of cefepime-taniborbactam to meropenem in 661 adults with cUTI.
Safety, Efficacy of Aminoglycosides or Polymyxin Monotherapy for Complicated UTI
Researchers conducted a study to assess the safety and efficacy of aminoglycosides or polymyxin monotherapy for the treatment of adults with complicated urinary tract infections caused by extensively drug-resistant Pseudomonas aeruginosa.
Probability of Progression to Complicated Urinary Tract Infection in Women With Antimicrobial-Resistant Isolates
Study finds that among women with uncomplicated urinary tract infection (UTI), those with antimicrobial-resistant isolates are at increased risk for progression to complicated UTI vs those with susceptible isolates.
ACP Releases Practice Advice for Short-Course Antibiotics in Common Infections
The American College of Physicians convened a panel to identify best practices for the use of short-course antibiotics in the management of common infections.
High Glycosuria Environment Allows for Increased Growth, Adherence of Group B Streptococcus
Investigators conducted a study to assess the effects of moderate glycosuria on group
B Streptococcus .
Treating Pyelonephritis Linked With Better Renal Graft Outcomes
Evidence of infection in urine was not significantly associated with graft survival, according to investigators.
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