Bone-Protecting Agents Reduce Fractures Associated With Treatment in Metastatic Castration-Resistant Prostate Cancer
The cumulative incidence of bone fractures was below 5% in BPA recipients.
ASCO 2021
Abiraterone Plus ADT and Docetaxel: A New SOC for Metastatic Castration-Sensitive Prostate Cancer?
Abiraterone prolonged radiographic progression-free survival by 2.5 years.
Pembrolizumab After RCC Surgery: Potential New Standard of Care
In the randomized phase 3 KEYNOTE-564 trial, pembrolizumab treatment after nephrectomy for clear cell RCC was associated with a 32% decreased risk of cancer recurrence or death compared with placebo.
Two-Drug Regimen Offers Better Health-Related Quality of Life in Advanced Renal Cell Carcinoma
The combination of lenvatinib and pembrolizumab improved health-related quality of life.
Targeted Radiotherapy Improves Outcomes in Previously Treated mCRPC
An investigational targeted radiotherapy added to standard of care improved survival in men with previously treated mCRPC.
Telaglenastat Fails to Improve Outcomes in Previously Treated Metastatic RCC
Adding telaglenastat to cabozantinib does not significantly prolong PFS compared with placebo plus cabozantinib in patients with mRCC whose disease progressed after 1 or 2 prior lines of systemic therapy.
Genomic Landscape of Prostate Cancer Differs by Ancestry, but Frequency of Actionable Alterations Is Similar
The frequency of targetable alterations was roughly 22% in patients of African ancestry and those of European ancestry.
TAK-700 Improves PFS, Not OS, Compared With Bicalutamide in Metastatic Hormone-Sensitive Prostate Cancer
TAK-700 plus ADT improved responses and progression-free survival compared with bicalutamide plus ADT.
Combo Continues to Show Superior Efficacy vs Sunitinib in Advanced Clear Cell Renal Cell Carcinoma
Pembrolizumab plus axitinib improved progression-free and overall survival.
ASCO: Bladder Sparing Studied in Muscle-Invasive Bladder Cancer
Transurethral resection then gemcitabine, cisplatin, plus nivolumab with intact bladder in selected patients studied in phase 2 trial
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