Researchers assessed the pharmacokinetics of piperacillin to determine whether standard dosing provides adequate exposure in critically ill children receiving continuous kidney replacement therapy.
Researchers conducted a study to assess the effect of an antibiotic stewardship program on the use of appropriate antibiotic therapy among patients with urinary tract infections in the ED.
In a study, IV fosfomycin appeared less effective than IV ceftriaxone or meropenem for bacteremic UTI caused by multidrug-resistant E. coli, but the drug may be considered for selected patients with these infections, according to investigators.
Researchers conducted a study to assess the safety and efficacy of aminoglycosides or polymyxin monotherapy for the treatment of adults with complicated urinary tract infections caused by extensively drug-resistant Pseudomonas aeruginosa.
Prescribers need to weigh the clinical benefits and potential cardiac risks of respiratory fluoroquinolones and amoxicillin-based antibiotics on an individual basis.
Study finds that among women with uncomplicated urinary tract infection (UTI), those with antimicrobial-resistant isolates are at increased risk for progression to complicated UTI vs those with susceptible isolates.
In a retrospective study of patients treated with vancomycin, acute kidney injury was 63% less likely to develop in those who took melatonin.
Researchers conducted a crossover study to determine whether probenecid and cephalexin administered together increases the clinical benefits of cephalexin.
Investigators conducted a cohort study that compared adverse effects and outcomes among patients with community-acquired urinary tract infection treated with cotrimoxazole vs fluoroquinolones.
The American College of Physicians convened a panel to identify best practices for the use of short-course antibiotics in the management of common infections.
