Diagnosis & Disease Information

Vitamin E-Coated Filters Fight Anemia

Long-term use of vitamin E-coated polysulfone membrane (VECM) dialysis filters may significantly improve hemoglobin levels and reduce requirements of erythropoietin (EPO), according to an Italian study.

Full Correction of Anemia May Be Bad

Achieving high hemoglobin levels in patients with CKD anemia may confer no cardiovascular benefit and could even increase the risk of death and cardiac problems, according to two studies published in the New England Journal of Medicine (2006;355:2071-2084;2085-2098).

Anemia Studies Not the Final Word

The recent publication of the CHOIR and CREATE studies in the New England Journal of Medicine questioning hemoglobin targets in dialysis patients have resulted in intense scrutiny of the relationship between Amgen, dialysis organizations, and physicians in the management of anemia.

Approvable Letter for Aranesp Extended Dosing

Amgen Inc., of Thousand Oaks, Calif., has received an approvable letter from the FDA for Aranesp (darbepoetin alfa) for de novo once-every-two-week dosing and for once-monthly maintenance dosing for non-dialysis CKD patients with anemia.

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