Little Added Risk When Hb Varies
The risk of death for patients with dialysis-related anemia is increased when hemoglobin levels are persistently low, not necessarily when they fluctuate.
Diagnosis & Disease Information
Novel Peptide-Based ESA Promising
BARCELONA—A novel peptide-based erythropoiesis-stimulating agent (ESA) called Hematide safely raises hemoglobin levels in anemic CKD patients and maintains stable hemoglobin levels in hemodialysis patients who switch to the drug from epoetin alfa, data suggest.
The Anemia Management Controversy
On September 11, 2007, an FDA panel of health experts declined to recommend the quasi-expected restrictions on the use of the erythropoietin stimulating agents (ESA) in CKD patients.
Once Monthly C.E.R.A. Found Beneficial
BARCELONA—Once-monthly dosing of continuous erythropoietin receptor activator (C.E.R.A.) maintains stable hemoglobin levels in CKD patients regardless of age, gender, or comorbidities, according to study data presented here at the 44th Congress of the European Renal Association-European Dialysis and Transplant Association.
CKD-Related Anemia Often Untreated
Only about one in 10 CKD-related outpatient visits for anemia management in the United States result in a prescription for an anemia medication, data show.
Untreated Anemia Increases Morbidity
CHICAGO—Diabetics with CKD whose anemia is untreated have twice the overall risk of CVD-related hospitalizations, according to data reported at the 67th Scientific Sessions of the American Diabetes Association.
Extended Epoetin Alfa Dosing Effects Similar in Diabetics
Patients with and without diabetes respond similarly to extended dosing of epoetin alfa as infrequently as once every four weeks, data show.
Epoetin Alfa Extended Dosing Is Effective
Starting anemia non-dialysis CKD patients on extended-dosing regimens of epoetin alfa can safely and effectively achieve target hemoglobin levels, data show.
Once-Monthly Darbepoetin Dosing Okay
Two studies suggest once-monthly dosing of darbepoetin alfa (Aranesp, Amgen) can effectively treat CKD anemia.
IV Iron Formulation Eases CKD Anemia
Ferumoxytol, a semi-synthetic iron oxide formulated with mannitol, may be a safe and effective IV iron treatment for anemia in CKD patients not on dialysis.
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