Bifunctional Biologic Gets Orphan Drug Status for Paroxysmal Nocturnal Hemoglobinuria
KP104 is a bifunctional, first-in-class biologic that works by selectively inhibiting the alternative and terminal pathways in the complement system.
Anemias
Anemia Ups Risk for Radical Cystectomy Complications
Anemia can identify patients at higher risk for radical cystectomy complications and may be useful in preoperative counseling, according to investigators.
Impact of Policy Changes for Anemia Care in Hemodialysis Examined
Changes in anemia care associated with lower risks for major adverse cardiovascular events, stroke, mortality, heart failure
Gout Common in Advanced Kidney Disease and Dialysis
Nearly 24% of patients with advanced CKD, including those on dialysis, have gout, according to a study.
Daprodustat Possibly an Oral Alternative to ESAs in Incident Dialysis
In a study of incident dialysis patients, the HIF-PHI agent daprodustat demonstrated safety and efficacy similar to that of the ESA darbepoetin alfa.
FDA Says No to Vadadustat Approval Due to Safety Concerns
The NDA submission included data from 36 clinical trials involving over 8000 patients.
Anaphylaxis Rare With IV Iron Use, But Risk Varies By Formulation
By clarifying the risk for anaphylaxis, study findings can contribute to the choice of IV iron preparations, according to investigators.
Red Cross Says Blood Shortage Is Worst in a Decade
Organization has had to limit blood product distributions to hospitals
Red Cross Says US Blood Supply at Dangerously Low Level
People who have received COVID-19 vaccines can donate blood and platelets as long as they are symptom-free
High-Dose IV Iron Reduces Myocardial Infarction in Hemodialysis
Until now, no other treatment has been shown to reduce heart attack risk in patients on dialysis.
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