Non-Standard Therapies Used in 20% of Localized High-Risk PCa Cases
Using EBRT alone or ADT alone for high-risk localized prostate cancer is associated with worse survival outcomes.
Androgen-deprivation Therapy
Lower Testosterone Threshold May Benefit ADT Recipients
New study shows prolonged time to development of castration-resistant prostate cancer among men with absolute testosterone levels below 20 ng/dL.
Low Carb Diet + Walking May Ease ADT’s Adverse Effects
In a small study, men on androgen deprivation therapy for prostate cancer lost weight and experienced improved hemoglobin A1C and lipid profiles.
Prostate Cancer ADT May Reduce Autoimmune Disease Risk
Androgen deprivation therapy recipients had a significantly lower risk for autoimmune diseases overall and for Graves’ disease, uveitis, and psoriasis.
New Surrogate Marker for ADT Evaluation Proposed
Time interval free of biochemical failure may be a potential surrogate end point in the setting of androgen-deprivation therapy evaluation in men with prostate cancer.
ADT May Be Less Beneficial for Gleason 9 to 10 Prostate Cancer
Men with Gleason score 9 to 10 prostate cancer derive no significant survival benefit from androgen deprivation therapy.
Androgen Deprivation Linked With Heart Failure
In a study, heart failure was nearly twice as likely to develop among ADT recipients compared with non-recipients.
Dementia Not Linked to ADT for Prostate Cancer
In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.
Prostate Cancer ADT Linked to Higher Risk of Liver Diseases
Men who received androgen deprivation therapy for prostate cancer were 54% more likely to be diagnosed with non-alcoholic fatty liver disease than those who did not, a study found.
Shorter ADT Course May Suffice for High-Risk Prostate Cancer
New study shows no significant difference in overall survival between 18 and 36 months of androgen deprivation therapy used in combination with radiation therapy.
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