Pretransplant Immunosuppression for Glomerulonephritis Ups Malignancy Risk
Patients receiving significant amount of immunosuppression prior to kidney transplantation should be counseled on these malignancy risks, according to investigators.
Diagnosis & Disease Information
FDA Approves Oral Daprodustat to Treat Anemia in Dialysis
The FDA approval of daprodustat is based on results from the ASCEND-D trial comparing daprodustat with ESAs.
Prostate Cancer ADT Increases Bone Fracture Risk
Investigators examined the risk of bone fracture associated with different forms of androgen deprivation therapy.
HIF-PHIs and ESAs Have Comparable Adverse Effects
Investigators report results from a systematic review and meta-analysis of data from 23 randomized controlled trials involving 15,144 patients with anemia of CKD.
5-ARIs Linked With Depression, But Not Suicide Risk
This Swedish population-based study has the largest sample size to date exploring these associations.
SGLT2 Inhibitor Plus MRA May Further Reduce Cardiovascular Risks
SGLT2 inhibitors and MRAs might provide complementary effects for organ protection, according to investigators.
Sick Day Medication Consensus Recommendations Issued
Guidance may help prevent serious adverse medication complications during acute illness leading to hospitalization or death.
Resistant Hypertension Effectively Treated With Novel Drug
Blocking the endothelin pathway could represent a new mode of action to lower blood pressure in resistant hypertension, according to investigators.
Trimethoprim-Sulfamethoxazole vs Amoxicillin Ups Hyperkalemia Risk
Trimethoprim-sulfamethoxazole is mostly excreted through the kidneys, and it can cause hyperkalemia by reducing potassium excretion.
Sodium Zirconium Cyclosilicate Reduces Tacrolimus Absorption
Tacrolimus exposure was reduced by approximately one-third when it was co-administered with the potassium binder sodium zirconium cyclosilicate, investigators reported.
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