ADPKD Outcomes Differ by Race
White patients with ADPKD may have advantages such as earlier predialysis care with referrals and preparation for dialysis and transplantation, according to investigators.
Diagnosis & Disease Information
Post-Kidney Transplant MACE Predicts Worse Survival
Kidney transplant recipients who had nonfatal MACE within the first year after transplant surgery, compared with those who did not, had a significantly lower 1-year survival rate (80.5% vs 97.4%).
Study Identifies Predictors of Rapid Renal Decline in ADPKD
Creatinine alone does not reliably predict renal decline in the AKPKD population, according to investigators.
ADPKD Progression to End-Stage Kidney Disease Varies by Race/Ethnicity
Autosomal dominant polycystic kidney disease progresses to kidney failure faster in Hispanic patients than in those of other races or ethnicities, a study found.
Patient Interviews Highlight Challenges in ADPKD Management
Nephrologists rarely explained the clinical meaning of rapid progression, according to patients.
ADPKD Death Rates Differ by Race, Ethnicity
Study findings fill an important knowledge gap in ADPKD mortality in the United States, according to researchers.
Urine-to-Plasma Urea Ratio Predicts ADPKD Progression
The early morning fasting urine-to-plasma urea ratio reflects the kidneys’ urine-concentrating capacity, which may decline early in ADPKD, according to investigators.
Lower Bicarbonate in ADPKD Linked to Worsening Kidney Outcomes
A study of patients with ADPKD found that each 1 mmol/L decrease in serum bicarbonate was significantly associated with a 21% increased risk for worsening kidney function.
Orphan Drug Status Granted to Potential Polycystic Kidney Disease Treatment
Autosomal dominant polycystic kidney disease (ADPKD) is caused by mutations of the PKD1 and PKD2 genes.
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