Therapeutic Peptide Granted Orphan Drug Status for Hepatorenal Syndrome
The Company is currently evaluating OCE-205 in a phase 2 trial in adults who have developed hepatorenal syndrome with acute kidney injury.
Acute Kidney Injury
Intervention Cuts Risk for AKI After Coronary Angiography
Reduced incidence of AKI seen in association with multifaceted intervention, including clinical decision support, audit, feedback
Unresolved Kidney Injury Ups Death Risk After COVID-19 Hospitalization
Research shows that acute kidney injury is a major contributor to death after hospital discharge for COVID-19 infection.
Study: RenalGuard Not Superior in Avoiding CIN in High-Risk Cases
Latest findings from a study of RenalGuard contrast with those of previous randomized controlled trials.
AKI-to-CKD Transition Predicts Higher Infection Risk
Following an episode of acute kidney injury, patients who transition to chronic kidney disease have a significant 1.5-fold increased long-term risk for infection, a study found.
Stopping RAS Inhibitors After AKI Ups Risk for Adverse Events
Findings may aid physicians in their clinical decision-making in the absence of randomized clinical trial data, according to investigators.
Kidney Function at 3 Months After AKI Is ‘Unreliable’ for Prognosis
Preserved kidney function at 3 months after AKI does not guarantee good kidney function over the long term, according to investigators.
Sickle Cell Trait, Kidney Conditions Linked With Poor COVID-19 Outcomes
Adults with sickle cell trait had a variety of preexisting kidney conditions that may have contributed to unfavorable outcomes following COVID-19 infection.
Consuming Coffee May Lower Risk for Acute Kidney Injury
Higher daily consumption tied to lower risk for new acute kidney injury diagnosis
Kidney Stress Biomarkers May Improve Severity Grading in Acute Kidney Injury
Tissue inhibitor of metalloproteinases 2 (TIMP-2) and insulinlike growth factor binding protein 7 (IGFBP7) could be used for AKI staging.
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