Multiparametric MRI demonstrating a small suspicious lesion in the right peripheral zone.
Multiparametric MRI demonstraing a small suspicious lesion in the right peripheral zone.
A 64-year-old man with rising PSA who had a previous negative prostate biopsy 3 years previously underwent a multiparametric MRI that demonstrates a PIRADS Score 4 lesion in the right peripheral zone.
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This case was prepared by Alexander Kutikov, MD, of Fox Chase Cancer Center in Philadelphia.
Siddiqui MM, Rais-Bahrami S, Turkbey B, et al. Comparison of MR/ultrasound fusion-guided biopsy with ultrasound-guided biopsy for the diagnosis of prostate cancer. JAMA 2015;313:390-397.
Schoots IG, Roobol MJ, Nieboer D, et al. Magnetic resonance imaging-targeted biopsy may enhance the diagnostic accuracy of significant prostate cancer detection compared to standard transrectal ultrasound-guided biopsy: a systematic review and meta-analysis. Eur Urol 2015;68:438-450.
A US/MRI fusion targeted biopsy results in upgrading in more than 30% of cases when compared to results of a 12-core standard template performed during the same session. However, at least about 10% of high-risk tumors are still missed by fusion techniques if a 12-core biopsy is omitted.