Dermatology
Are You Confident of the Diagnosis? Lichen planopilaris (LPP) is a rare chronic scarring folliculitis of the scalp of unknown cause (Figure 1). It is considered a primary scarring alopecia since the follicle itself is targeted by inflammatory cells and scarring occurs first and primarily around the follicular unit. Because T cells are the overwhelmingly…
Drug Monograph
Pioglitazone (as HCl), metformin HCl; 15mg/500mg, 15mg/850mg; tabs.
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Hospital Medicine
Nonalcoholic Steatohepatitis I. What every physician needs to know. Nonalcoholic fatty liver disease (NAFLD) represents a spectrum of liver disease characterized by accumulation of triglycerides within the hepatocyte. This ranges from bland steatosis or fat accumulation without inflammation to nonalcoholic steatohepatitis (NASH) which can go on to cause fibrosis and eventually cirrhosis. Continue Reading II.…
Cardiology
General (including evidence of efficacy) Residual cardiac risk with mixed dyslipidemia An elevated level of low density lipoprotein cholesterol (LDL-C) is established as a risk factor for the development of coronary and peripheral atherosclerotic vascular disease. Numerous randomized, prospective trials using 3-hydroxy-3-methyl-glutaryl coenzyme A (HMG-CoA) reductase inhibitors (statins) have demonstrated the ability of these agents…
Annual Dialysis Conference
SEATTLE—Dialysis patients are at increased risk for fractures, and these fractures are associated with a higher morbidity and mortality compared with fractures in the general population, according to nephrologist Jean Holley, MD, Clinical Professor of Medicine at the University of Illinois at Urbana-Champaign.
Diabetes
Some therapies harbor cardiovascular benefits while others may pose significant risks.
Diabetes
The AHA released a statement focusing on the importance of managing cardiovascular risk factors in patients with type 2 diabetes.
Dermatology
Are You Confident of the Diagnosis? Polycystic ovarian syndrome (PCOS) presents with a variable constellation of symptoms. Establishing precise diagnostic criteria has been challenging. In 2003, the Rotterdam Consensus Group defined PCOS by the presence of two out of three of the following factors: oligo- or anovulation, signs of hyperandrogenemia, and polycystic ovaries on ultrasound…
Endocrinology Metabolism
What every physician needs to know When to initiate pharmacologic therapy in type 2 diabetes mellitus Healthy lifestyle changes, including diet and exercise, remain the cornerstone of successful therapy for type 2 diabetes mellitus. However, in the past, initiation of pharmacologic therapy was often delayed to allow a patient to attempt those modifications. Currently, both…
Expert Perspectives
To shed light on this complex subject, MPR interviewed Joshua D Brown, PharmD, PhD, Assistant Professor, Pharmaceutical Outcomes & Policy.
