Radiotherapy

Hypofractionated Radiation OK for Localized Prostate Cancer

Hypofractionated Radiation OK for Localized Prostate Cancer

New multidisciplinary guideline for early-stage prostate cancer developed by 3 professional societies.

Radiation Ups Survival When PCa Metastatic Burden Is Low

Radiation Ups Survival When PCa Metastatic Burden Is Low

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The 3-year survival rate was 81% for patients who underwent EBRT plus standard care vs 73% for those who had standard care alone.

Long-Term Benefit for Stereotactic Radiation in Prostate Cancer

Long-Term Benefit for Stereotactic Radiation in Prostate Cancer

Trials show high survival rates, freedom from recurrence for low-, intermediate-risk prostate cancer.

Light Use of Topical Skin Tx Before Radiotherapy Seems Safe

Light Use of Topical Skin Tx Before Radiotherapy Seems Safe

Radiation dose not impacted with light or moderate use of skin treatments, regardless of beam energy, incidence

Senior Cancer Patients Also Benefit From Palliative Radiotherapy

Senior Cancer Patients Also Benefit From Palliative Radiotherapy

Benefit of palliative radiation for bone metastasis across age groups; older age should not preclude tx.

Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

Dose-Escalated RT Does Not Improve Survival in Intermediate-Risk PCa

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Researchers observed reductions in biochemical failure and distant metastasis rates in patients who had dose-escalated radiation therapy.

EBRT+BT+ADT May Be Optimal for High-Grade PCa

EBRT+BT+ADT May Be Optimal for High-Grade PCa

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In a study, extremely dose-escalated radiotherapy combined with androgen deprivation therapy offered the best cancer-specific survival among men with Gleason 9-10 prostate cancer.

LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

LDR Brachytherapy for Prostate Cancer Offers Excellent Survival

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In a study, the 17-year prostate cancer-specific and biochemical failure-free survival rates were 97% and 79%, respectively.

Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

Adjuvant Better Than Early Salvage RT for Some High-risk PCa Patients

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Adjuvant radiotherapy was associated with lower risks for biochemical failure and distant metastases and increased overall survival in patients with adverse pathologic features found after radical prostatectomy.

Adjuvant Radiation Therapy May Improve Survival After Cystectomy

Adjuvant Radiation Therapy May Improve Survival After Cystectomy

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The locoregional recurrence-free survival rate at 2 years was significantly higher for patients treated with chemotherapy plus RT versus those treated with chemotherapy alone.

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

Odds of Prostate Cancer Treatment With SBRT Linked to Travel Distance

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Patients who have to travel longer distances for prostate cancer treatment are more likely to receive stereotactic body radiotherapy.

Cancer Treatments Can Have Effects on Aging Phenotypes

Cancer Treatments Can Have Effects on Aging Phenotypes

Certain chemotherapies might shorten telomeres and alter microRNA.

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

Optimal Salvage Treatment for Radiorecurrent PCa Still Unclear

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Definitive comparative effectiveness data are lacking for salvage prostatectomy or salvage cryotherapy.

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

Smaller Difference in Prostate Cancer Death Risk Found Between RT, RP

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Among patients with high-risk prostate cancer, investigators observe no significant difference in cancer-related death risk between radiotherapy and radical prostatectomy.

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

MRI Predicts Outcomes of Prostate Cancer Salvage Radiotherapy

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A negative mpMRI is associated with a higher risk for PSA recurrence and metastasis following salvage radiotherapy for recurrent prostate cancer after radical prostatectomy.

Surgery vs Radiation for High-Risk Prostate Cancer

Surgery vs Radiation for High-Risk Prostate Cancer

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Physicians who treat patients with high-risk prostate cancer remain uncertain as to the optimal treatment approach, in part due to difficulty in interpreting study data.

Brachytherapy + EBRT for High-Risk PCa Offers 'Excellent' Outcomes

Brachytherapy + EBRT for High-Risk PCa Offers 'Excellent' Outcomes

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Biochemical failure and prostate cancer-specific mortality rates were 13.3% and 4.9% at 10 years, respectively.

IMRT for Prostate Cancer Radiation Therapy Soars

IMRT for Prostate Cancer Radiation Therapy Soars

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Use of intensity-modulated radiation therapy for prostate cancer increased from 3.5% to 64% from 2002 to 2012.

Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

Toxicity Similar for 6- and 2- Fraction HDR Brachytherapy in PCa

The researchers found that there was no difference between the 6- and 2-fraction groups in baseline and post-implantation IPSS scores.

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

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Patients are more likely to receive intensity-modulated radiation therapy if they are managed by urology practices with an ownership interest in the modality, study finds.

Bladder Preservation Therapy Linked With Reduced Survival in MIBC

Bladder Preservation Therapy Linked With Reduced Survival in MIBC

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Radical cystectomy is associated with better survival, but findings suggest BPT may produce acceptable oncologic outcomes in appropriately selected patients.

Positive Lymph Node Prostate Cancer Care Patterns Characterized

Positive Lymph Node Prostate Cancer Care Patterns Characterized

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63% of patients were managed initially with observation.

Post-RP Radiotherapy Benefits Selected Men With Elevated PSA

Post-RP Radiotherapy Benefits Selected Men With Elevated PSA

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Radiotherapy for prostate cancer patients with persistently elevated PSA after radical surgery improved survival only among those with worse pathologic characteristics.

Surgery May Offer Better Survival for Younger Men With High-risk PCa

Surgery May Offer Better Survival for Younger Men With High-risk PCa

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Younger patients who chose surgery vs radiation for initial treatment had a 48% survival advantage.

Single Radiation Dose Can Ease Spinal Cord Compression

Single Radiation Dose Can Ease Spinal Cord Compression

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New findings establish single-dose radiotherapy as the standard of care for metastatic spinal canal compression, at least for patients with a short life expectancy, researcher says.

Diminished QOL Reported More Than 10 Years After PCa Treatment

Diminished QOL Reported More Than 10 Years After PCa Treatment

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Urinary incontinence and diminished sexual function were common after a median follow-up of nearly 15 years, study finds.

Yoga May Relieve Symptoms of Prostate Cancer Radiation Tx

Yoga May Relieve Symptoms of Prostate Cancer Radiation Tx

Men who attended yoga classes had less fatigue and better sexual and urinary function than those in the comparison group.

Prostate Cancer Treatment Prolongs Survival

Prostate Cancer Treatment Prolongs Survival

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Study compared PCa patients who underwent surgery or radiation treatment with a matched group of non-cancer controls.

Radiation Therapy Reduces Pain From Bone Metastases

Radiation Therapy Reduces Pain From Bone Metastases

A single 8-Gy radiotherapy dose for bone metastases should be offered to all patients, even those with poor survival.

PCa Salvage Radiation Plus Anti-Androgen Therapy Improves Outcomes

PCa Salvage Radiation Plus Anti-Androgen Therapy Improves Outcomes

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Combined treatment for recurrent prostate cancer after radical prostatectomy results in decreased long-term all-cause and cancer-specific mortality.

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