Prostate Cancer

Statins Plus ADT May Up Survival in Advanced Prostate Cancer

Statins Plus ADT May Up Survival in Advanced Prostate Cancer

By

Statin use by men receiving androgen deprivation therapy for advanced PCa was associated with decreased risk of overall and cancer-specific mortality.

Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Mean 2.9 years gained after 23 years of follow-up among men with localized prostate cancer

Visual Registration + Image Fusion Best for Targeted Biopsy

Visual Registration + Image Fusion Best for Targeted Biopsy

Combination of the strategies identifies the most clinically important prostate cancers.

Prostate Cancer Linked to Inflammatory Bowel Disease

Prostate Cancer Linked to Inflammatory Bowel Disease

By

IBD is associated with a nearly 5-fold increased risk of prostate cancer, study finds.

Testosterone Measurements, TRT Prescribing Infrequent in PCa Care

Testosterone Measurements, TRT Prescribing Infrequent in PCa Care

By

More than half of UK specialists surveyed said measuring testosterone levels in patients with nonmetastatic prostate cancer was not their routine practice.

ADT May Be Less Beneficial for Gleason 9 to 10 Prostate Cancer

ADT May Be Less Beneficial for Gleason 9 to 10 Prostate Cancer

By

Men with Gleason score 9 to 10 prostate cancer derive no significant survival benefit from androgen deprivation therapy.

Ultrasound + MRI Improves High-Grade Prostate Cancer Detection

Ultrasound + MRI Improves High-Grade Prostate Cancer Detection

By

Well demarcated hypoechoic areas in suspicious regions on MRI identify men more likely to have Gleason 7 or higher prostate cancer found on biopsy.

Prostate Cancer Risk Lower in Long-Term Users of Lipid-Lowering Drugs

Prostate Cancer Risk Lower in Long-Term Users of Lipid-Lowering Drugs

By

In a study, taking lipid-lowering drugs for 10 or more years was associated with a 32% lower risk prostate cancer.

Delayed Prostate Cancer Treatment May Up Relapse Risk

Delayed Prostate Cancer Treatment May Up Relapse Risk

By

Patients whose radical prostatectomy was delayed more than 6 months had a nearly 2-fold increased risk of biochemical recurrence, a study found.

Very High-Risk Prostate Cancer Criteria Validated as a Risk Stratum

Very High-Risk Prostate Cancer Criteria Validated as a Risk Stratum

By

Men with very high-risk (VHR) PCa are more likely to have adverse pathologic features and outcomes after radical prostatectomy than those with high-risk but not VHR PCa.

Surgery, Radiation Regimens for High-Grade PCa Offer Similar Outcomes

Surgery, Radiation Regimens for High-Grade PCa Offer Similar Outcomes

By

Study compared radical prostatectomy plus adjuvant EBRT or ADT, or both, with a triple combination of EBRT, brachytherapy, and ADT for Gleason score 9-10 prostate cancer.

Salvage Prostatectomy May Benefit Some Prostate Cancer Patients

Salvage Prostatectomy May Benefit Some Prostate Cancer Patients

By

Study of men who underwent salvage radical prostatectomy for radiorecurrent prostate cancer found a 10-year rate of biochemical progression-free survival of 33%.

Extraprostatic Extension Indicates Aggressive Prostate Cancer

Extraprostatic Extension Indicates Aggressive Prostate Cancer

By

Many patients with extraprostatic extension on biopsy experience biochemical recurrence after surgery and require early multi-modal therapy.

Androgen Deprivation Linked With Heart Failure

Androgen Deprivation Linked With Heart Failure

By

In a study, heart failure was nearly twice as likely to develop among ADT recipients compared with non-recipients.

Study: Microarray CCP Scores Not a Substitute for qRT-PCR

Study: Microarray CCP Scores Not a Substitute for qRT-PCR

By

Investigators conclude that microarray-generated cell cycle progression score should not be assumed to be a valid surrogate for qRT-PCR-generated scores.

Prostate Cancer Linked to Greater Fat, Fatty Acid Intake

Prostate Cancer Linked to Greater Fat, Fatty Acid Intake

By

As stearic acid and total fatty acid intake increased from one quintile to the next, prostate risk increased by 23% and 21%, respectively.

Prostate Cancer Focal Ablation Can Be a Reasonable Option

Prostate Cancer Focal Ablation Can Be a Reasonable Option

By

Patient selection and physician-patient commitment to careful follow-up surveillance are key.

'Real-World' Study Characterizes PCa Active Surveillance

'Real-World' Study Characterizes PCa Active Surveillance

By

Findings from a large contemporary cohort of men on active surveillance for prostate cancer shows that disease characteristics, not socioeconomic factors, are driving prostate cancer management.

Barriers to Prostate Cancer Research in Black Men Identified

Barriers to Prostate Cancer Research in Black Men Identified

Mistrust, lack of knowledge, unfavorable attitudes are barriers to genomic testing, study participation

Hypofractionated Radiation OK for Localized Prostate Cancer

Hypofractionated Radiation OK for Localized Prostate Cancer

New multidisciplinary guideline for early-stage prostate cancer developed by 3 professional societies.

Radiation Ups Survival When PCa Metastatic Burden Is Low

Radiation Ups Survival When PCa Metastatic Burden Is Low

By

The 3-year survival rate was 81% for patients who underwent EBRT plus standard care vs 73% for those who had standard care alone.

Long-Term Benefit for Stereotactic Radiation in Prostate Cancer

Long-Term Benefit for Stereotactic Radiation in Prostate Cancer

Trials show high survival rates, freedom from recurrence for low-, intermediate-risk prostate cancer.

LDR Brachytherapy for PCa Yields Excellent Outcomes

LDR Brachytherapy for PCa Yields Excellent Outcomes

By

Long-term data show a local disease recurrence rate of 2.1% at 10 years.

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

By

Among prostate cancer patients, androgen deprivation therapy (ADT) recipients are 34% more likely to experience any osteoporotic fracture than those who do not receive ADT.

Genetic Differences in Prostate Cancer Pinpointed in Black Men

Genetic Differences in Prostate Cancer Pinpointed in Black Men

By

New findings could help explain why men of African ancestry are more likely than white men to die from prostate cancer.

Elevated PSA at Midlife Predicts Aggressive Prostate Cancer in Blacks

Elevated PSA at Midlife Predicts Aggressive Prostate Cancer in Blacks

By

A midlife PSA value above the 90th percentile was associated with greater risk of total and aggressive prostate cancer in black men.

Dementia Not Linked to ADT for Prostate Cancer

Dementia Not Linked to ADT for Prostate Cancer

By

In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.

Bladder Cancer Risk Higher With Radiation Therapy for Prostate Cancer

Bladder Cancer Risk Higher With Radiation Therapy for Prostate Cancer

By

In a recently published study, external beam radiation therapy for localized prostate cancer was associated with a 35% increased risk of bladder cancer compared with radical prostatectomy.

Simple Clinical Factors May Aid Prognosis in nmCRPC

Simple Clinical Factors May Aid Prognosis in nmCRPC

By

A combination of age, comorbidity, and PSA doubling time can risk stratify cause of death among men with non-metastatic castration-resistant prostate cancer, study suggests.

Cancer Risk Varies for Hispanics, Including in Puerto Rico

Cancer Risk Varies for Hispanics, Including in Puerto Rico

Men in Puerto Rico have higher prostate cancer incidence rates than other Hispanics, non-Hispanic whites.

Sign Up for Free e-newsletters