Prostate Cancer

LDR Brachytherapy for PCa Yields Excellent Outcomes

LDR Brachytherapy for PCa Yields Excellent Outcomes

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Long-term data show a local disease recurrence rate of 2.1% at 10 years.

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

Prostate Cancer ADT Ups Osteoporotic Fracture Risk

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Among prostate cancer patients, androgen deprivation therapy (ADT) recipients are 34% more likely to experience any osteoporotic fracture than those who do not receive ADT.

Genetic Differences in Prostate Cancer Pinpointed in Black Men

Genetic Differences in Prostate Cancer Pinpointed in Black Men

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New findings could help explain why men of African ancestry are more likely than white men to die from prostate cancer.

Elevated PSA at Midlife Predicts Aggressive Prostate Cancer in Blacks

Elevated PSA at Midlife Predicts Aggressive Prostate Cancer in Blacks

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A midlife PSA value above the 90th percentile was associated with greater risk of total and aggressive prostate cancer in black men.

Dementia Not Linked to ADT for Prostate Cancer

Dementia Not Linked to ADT for Prostate Cancer

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In a study, androgen deprivation therapy did not increase risks for vascular or any other form of dementia among men with prostate cancer who underwent definitive radiation therapy.

Bladder Cancer Risk Higher With Radiation Therapy for Prostate Cancer

Bladder Cancer Risk Higher With Radiation Therapy for Prostate Cancer

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In a recently published study, external beam radiation therapy for localized prostate cancer was associated with a 35% increased risk of bladder cancer compared with radical prostatectomy.

Simple Clinical Factors May Aid Prognosis in nmCRPC

Simple Clinical Factors May Aid Prognosis in nmCRPC

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A combination of age, comorbidity, and PSA doubling time can risk stratify cause of death among men with non-metastatic castration-resistant prostate cancer, study suggests.

Cancer Risk Varies for Hispanics, Including in Puerto Rico

Cancer Risk Varies for Hispanics, Including in Puerto Rico

Men in Puerto Rico have higher prostate cancer incidence rates than other Hispanics, non-Hispanic whites.

The Growing Challenge of Advanced Prostate Cancer Clinics

The Growing Challenge of Advanced Prostate Cancer Clinics

With an ever-expanding array of options for treating advanced prostate cancer, it is important to remain focused on the best treatment path for each patient.

Bladder Cancer Risk Not Lowered With Androgen Deprivation

Bladder Cancer Risk Not Lowered With Androgen Deprivation

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In a study, men with prostate cancer who received androgen deprivation therapy did not have a lower subsequent risk of developing bladder cancer.

Cryoablation a Possible Alternative Prostate Cancer Treatment

Cryoablation a Possible Alternative Prostate Cancer Treatment

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Medium-term oncologic results are comparable to those of radical prostatectomy and radiation therapy, according to investigators.

Study: Private Payer Coverage of Prostate MRI Lagging

Study: Private Payer Coverage of Prostate MRI Lagging

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Only 11% of private insurers in the United States cover prostate MRI in biopsy-naïve patients with suspect prostate cancer.

Surgery + Radiation for Advanced PCa Offers Better Survival

Surgery + Radiation for Advanced PCa Offers Better Survival

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Radical prostatectomy plus adjuvant radiotherapy is associated with better cancer-specific and overall survival than radiotherapy plus androgen deprivation therapy in patients with locally or regionally advanced prostate cancer.

Magnetic Resonance Imaging Prior to Initial Prostate Biopsy

Magnetic Resonance Imaging Prior to Initial Prostate Biopsy

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MRI of the prostate prior to a biopsy of the gland improves prostate cancer detection, but insurers resist paying for it.

High Cholesterol Ups Risk of Aggressive Prostate Cancer

High Cholesterol Ups Risk of Aggressive Prostate Cancer

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Men in the highest vs lowest tertile of total cholesterol had a 42% increased risk of Gleason 8-10 prostate cancer, Finnish study finds.

Study Zeroes in on Cause of Castration-Resistant Prostate Cancer

Study Zeroes in on Cause of Castration-Resistant Prostate Cancer

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Some prostate cancer cells lack androgen receptor, and they proliferate faster than those that express androgen receptor under androgen-deficient conditions.

Annual PSA Screening Best for Reducing Prostate Cancer Deaths

Annual PSA Screening Best for Reducing Prostate Cancer Deaths

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A study of 400,887 men in an integrated health system, the first to evaluate various PSA screening intervals and age groups, concluded that yearly screening is the interval of choice.

Apalutamide Preserves HRQoL in Nonmetastatic CRPC

Apalutamide Preserves HRQoL in Nonmetastatic CRPC

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New analysis of the SPARTAN trial shows that apalutamide maintains health-related quality of life while lowering the risk of metastasis.

Prostate Cancer Radiotherapy Effective Long-Term

Prostate Cancer Radiotherapy Effective Long-Term

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Australian study shows 8-year overall survival and biochemical relapse-free rates of 78.4% and 68.1%, respectively.

Prostate Cancer ADT Linked to Higher Risk of Liver Diseases

Prostate Cancer ADT Linked to Higher Risk of Liver Diseases

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Men who received androgen deprivation therapy for prostate cancer were 54% more likely to be diagnosed with non-alcoholic fatty liver disease than those who did not, a study found.

Prostate Cancer AS Loss to Follow-Up Risk at 2 Years Estimated at 10%

Prostate Cancer AS Loss to Follow-Up Risk at 2 Years Estimated at 10%

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The risk being lost to follow-up while on active surveillance for prostate cancer is higher among blacks than whites, according to a study.

Prazosin May Lower Prostate Cancer Recurrence Risk After Radiotherapy

Prazosin May Lower Prostate Cancer Recurrence Risk After Radiotherapy

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LUTS treatment with the alpha-blocker prazosin was associated with significantly lower 2- and 5-year biochemical recurrence rates vs tamsulosin and non-use of alpha-blockers.

Advances in Imaging, Therapies Bode Well for nmCRPC Management

Advances in Imaging, Therapies Bode Well for nmCRPC Management

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Novel imaging and tumor biomarker assays are likely to define non-metastatic castration-resistant prostate cancer more accurately, authors of new review state.

LDR Brachytherapy Beneficial In High-Risk Prostate Cancer

LDR Brachytherapy Beneficial In High-Risk Prostate Cancer

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Low-dose-rate brachytherapy is associated with excellent long-term biochemical control and survival, new study finds.

Prostate Cancer Risk Lower In Men in Physically Demanding Jobs

Prostate Cancer Risk Lower In Men in Physically Demanding Jobs

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Even low cumulative exposure to physical strain at work is associated with a decreased risk of prostate cancer, study finds.

Prostate MRI Use Ups Odds of Prostate Cancer Observation

Prostate MRI Use Ups Odds of Prostate Cancer Observation

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In a study, men with low-risk prostate cancer were nearly 2-fold more likely to be managed with observation if they had a prostate MRI during the diagnostic work-up.

Decline in Surgical Overtreatment of Prostate Cancer Reported

Decline in Surgical Overtreatment of Prostate Cancer Reported

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At a major tertiary referral center, the use of radical prostatectomy for insignificant prostate cancer decreased from 15% in 2009 to 3% in 2016, a study found.

Prostate Cancer Diagnoses Increase Men's Suicide Risk

Prostate Cancer Diagnoses Increase Men's Suicide Risk

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A patient's risk of suicide is doubled within the first year following a prostate cancer diagnosis, according to a new meta-analysis.

Obese Prostate Cancer Patients Do Worse After Radical Prostatectomy

Obese Prostate Cancer Patients Do Worse After Radical Prostatectomy

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Study of Korean radical prostatectomy patients showed that those who were obese had significant increased odds of biochemical recurrence and cancer-specific mortality

Cytoreductive Surgery for Metastatic PCa Linked to More Complications

Cytoreductive Surgery for Metastatic PCa Linked to More Complications

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Cytoreductive radical prostatectomy (RP) for metastatic prostate cancer (PCa) is associated with higher complication rates and longer hospital stays than RP for non-metastatic PCa.

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