Prostate Cancer

Prostate Biopsy Complications Deter Patients From Re-Biopsy

Prostate Biopsy Complications Deter Patients From Re-Biopsy

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Study participants with acute urinary retention after TRUS-guided prostate biopsy were 4.5 times more likely to skip a recommended re-biopsy than men who had no initial biopsy-related complications.

 Long-Term Data Support Finasteride for PCa Prevention

Long-Term Data Support Finasteride for PCa Prevention

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Clinicians can rest easier about recommending finasteride to more men, according to experts.

Prostate Cancer Treatment Side Effects Linked to Distress

Prostate Cancer Treatment Side Effects Linked to Distress

Those with worse emotional distress also report worse urinary, sexual, bowel functions.

Biparametric MRI Improves Detection of Significant PCa

Biparametric MRI Improves Detection of Significant PCa

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If externally validated, bpMRI could be used to triage men for prostate biopsy.

Abiraterone for mCRPC May Benefit Blacks More Than Whites

Abiraterone for mCRPC May Benefit Blacks More Than Whites

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Abiraterone plus prednisone was associated with significantly greater PSA progression-free survival among patients who are black compared with white patients.

Robotics Involved in Most Urologic Cancer Surgeries

Robotics Involved in Most Urologic Cancer Surgeries

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In 2015, 69% of surgeries for prostate, bladder, and kidney cancer were performed with robotic assistance, a new meta-analysis shows.

Enzalutamide for Advanced Prostate Cancer Does Not Worsen HRQoL

Enzalutamide for Advanced Prostate Cancer Does Not Worsen HRQoL

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Enzalutamide decreases the risk of clinically meaningful deterioration in HRQoL compared with placebo in men with non-metastatic CRPC, new study finds.

AUA Updates Castration-Resistant Prostate Cancer Clinical Guideline

AUA Updates Castration-Resistant Prostate Cancer Clinical Guideline

"We are confident this guideline is fully aligned with the latest science on treatments for patients with non-metastatic and metastatic CRPC," said Michael Cookson, MD, member of the 2018 amendment panel.

PSA Level 3 Months After Radiation Tx May Predict Outcome

PSA Level 3 Months After Radiation Tx May Predict Outcome

Findings for men with intermediate- and high-risk prostate cancer.

Current Smokers at Risk for Worse Prostate Cancer Outcomes

Current Smokers at Risk for Worse Prostate Cancer Outcomes

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In a meta-analysis, smokers had an 89% greater risk of dying from prostate cancer compared with nonsmokers.

FDA Approves Yonsa for Metastatic Castration-Resistant Prostate Cancer

FDA Approves Yonsa for Metastatic Castration-Resistant Prostate Cancer

The approval of Yonsa was based on 2 randomized, placebo-controlled, multicenter Phase 3 studies in patients with mCRPC.

From 2008 to 2014, Prostate Cancer Testing, Treatment Down

From 2008 to 2014, Prostate Cancer Testing, Treatment Down

Sharpest decrease seen in privately insured men after 2011.

Laser Focal Ablation of Prostate Cancer Improves Outcomes

Laser Focal Ablation of Prostate Cancer Improves Outcomes

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Men with low-risk PCa who underwent partial gland ablation with vascular-targeted photodynamic therapy were less likely than those on AS to require radical treatment.

Node-Positive Prostate Cancer on the Rise

Node-Positive Prostate Cancer on the Rise

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The percentage of prostate cancer patients with positive lymph nodes increased from 2.4% in 2010 to 4.7% in 2014.

BPH, Cancers Linked to Peyronie's Disease

BPH, Cancers Linked to Peyronie's Disease

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Men with Peyronie's disease have elevated risks of benign prostatic hyperplasia, prostatitis, and testis and prostate cancer, new studies reveal.

Testosterone Therapy Safe Despite Prostate Cancer History

Testosterone Therapy Safe Despite Prostate Cancer History

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Findings from the largest study to date examining the effect of TRT in prostate cancer patients build on previous evidence showing that the treatment does not affect disease progression risk.

Incontinence, Impotence Risk After RP Linked to Metabolic Syndrome

Incontinence, Impotence Risk After RP Linked to Metabolic Syndrome

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At 1 year post-op, patients with MetS prior to prostate surgery had a significantly lower continence rate than those without MetS (75.4% vs 82.6%).

Clinical Variables Predict Radiographic Progression in mCRPC

Clinical Variables Predict Radiographic Progression in mCRPC

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Extent of disease and change in PSA were the strongest predictors of disease progression in men with chemotherapy-naïve mCRPC treated with abiraterone.

Focal vs Total PCa Cryoablation Better for Sexual Function

Focal vs Total PCa Cryoablation Better for Sexual Function

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Oncologic outcomes are similar for focal and total cryoablation for localized prostate cancer, but patients report significantly better sexual function after focal cryoablation.

Negative Confirmatory Biopsy Predicts Lower PCa Progression Risk

Negative Confirmatory Biopsy Predicts Lower PCa Progression Risk

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Men on active surveillance for prostate cancer who had a negative confirmatory biopsy experienced an 88% decreased risk of progression to treatment.

Prostate Cancer Recurrence Risk Lower With Anterior Tumors

Prostate Cancer Recurrence Risk Lower With Anterior Tumors

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Following laparoscopic radical prostatectomy, men with posterior index tumors had 76% increased risk of biochemical recurrence vs those with anterior prostate tumors.

Gleason Score at Surgical Margin Affects BCR Risk

Gleason Score at Surgical Margin Affects BCR Risk

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Gleason score at the margin can better stratify biochemical recurrence-free rates, according to study findings.

AS May Be Safe for Selected Men With Gleason 3+4 Prostate Cancer

AS May Be Safe for Selected Men With Gleason 3+4 Prostate Cancer

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Men with Gleason 6 and Gleason 3+4 prostate cancer who undergo radical prostatectomy after a period on active surveillance have similar surgical outcomes.

Novel Blood Test Improves Detection of High-Grade Prostate Cancer

Novel Blood Test Improves Detection of High-Grade Prostate Cancer

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IsoPSA can correctly rule out high-grade prostate cancer 93% of the time and thus has the potential to reduce the number of unnecessary prostate biopsies.

Optimal Post-Radical Prostatectomy Follow-up Schedule Proposed

Optimal Post-Radical Prostatectomy Follow-up Schedule Proposed

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Investigators suggest PSA testing frequencies based on post-operative baseline PSA.

Overall, Drinking Wine Does Not Impact Prostate Cancer Risk

Overall, Drinking Wine Does Not Impact Prostate Cancer Risk

Findings show small increased risk with white wine, decreased risk with red wine

Predictors of Adverse Pathology After Prostate Cancer Surgery ID'd

Predictors of Adverse Pathology After Prostate Cancer Surgery ID'd

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High PSA levels and larger number of positive biopsy cores are associated with positive surgical margins and extracapsular extension/seminal vesicle invasion after radical prostatectomy.

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

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Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Cancer Incidences and Burden Expected to Shift in HIV-Positive

Prostate and lung cancer expected to emerge as the most common types by 2030.

USPSTF Updates Prostate Cancer Screening Recommendations

USPSTF Updates Prostate Cancer Screening Recommendations

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The new statement emphasizes shared decision-making on screening for men aged 55 to 69 years who are at average risk for prostate cancer.

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