Multiparametic MRI findings added to conventional clinical predictors decreases the number of false-positive biopsy results without increasing the number of clinically significant tumors left undiagnosed, study finds.
Apalutamide prolonged metastasis-free survival by 2 years compared with placebo.
Added to hormone therapy, docetaxel offers a cost effective way to prolong hormone-sensitive disease and improve quality of life years, especially among men with non-metastatic disease, study finds.
Trials sponsored by academic investigators, cooperative groups more likely to use these criteria
In a small phase 2 study of overweight men with recurrent prostate cancer, consuming less than 20 grams of carbohydrates a day resulted in profound weight loss.
Metastasis and death are more likely to occur among patients with relatively high PSA levels at diagnosis of nmCRPC and rising PSA levels during follow-up.
Multiparametric MRI has high positive and negative predictive values for extracapsular extension, seminal vesicle invasion, lymph node involvement, and high-risk Gleason score.
In a study, nearly 20% of radical cystectomy patients were readmitted for complications within 90 days compared with 1.9% and 5.9% for radical prostatectomy and radical nephrectomy, respectively.
Among men who had PSA failure following radiation therapy for localized PCa, those with a long PSA doubling time had an increased risk of PCa mortality if they started androgen-deprivation therapy later.
Black men undergoing radical prostatectomy for prostate cancer are more likely to have indications for adjuvant radiotherapy compared with white men.
Statin use is associated with greater overall survival among men with metastatic castration-resistant prostate cancer and improved survival among patients with high-risk prostate cancer.
In a study, a negative confirmatory prostate biopsy in prostate cancer patients on active surveillance predicts a lower risk of progressing to treatment.
In separate studies, apalutamide and enzalutamide prolonged metastasis-free survival in men with non-metastatic castration-resistant prostate cancer.
In a study of hypogonadal men, those who received testosterone therapy had a lower incidence of prostate cancer than those who did not.
The investigators observed no difference in mortality between BT alone and BT plus ADT and/or EBRT supplemental therapy.
The technology facilitates teaching of advanced surgical skills, delivery of care to underserved
Investigators have explored various strategies to prevent lymphoceles from forming.
In a study, the 17-year prostate cancer-specific and biochemical failure-free survival rates were 97% and 79%, respectively.
Adjuvant radiotherapy was associated with lower risks for biochemical failure and distant metastases and increased overall survival in patients with adverse pathologic features found after radical prostatectomy.
Following radical prostatectomy, higher BMI increases risk of recurrence for prostate cancer.
Androgen-deprivation therapy without estrogen is associated with a significant 43% increased risk of thromboembolic events, meta-analysis shows.
In a meta-analysis, the risk of infectious complications was 78% lower with fosfomycin trometamol versus fluoroquinolones in men undergoing TRUS-guided prostate biopsy.
Clinicians need to ask about cancers among members of the maternal and paternal sides of a family.
In a single center study, asymptomatic bacteriuria resolved before prostate biopsy, without additional treatment.
Polygenic hazard score can guide screening based off predicted prostate cancer diagnosis age.
A study showed longer survival among patients with metastatic hormone-sensitive prostate cancer who achieved a PSA level of 0.2 ng/mL or less 7 months after initiating ADT.
Study finds that closely adhering to a Mediterranean-style diet possibly protects men from aggressive and advanced prostate cancer.
Each 10 mg/dL increase in serum levels of total and HDL cholesterol are associated with a significant 5% and 14% increased risk of high-grade PCa, respectively.
Multiparametric magnetic resonance imaging in conjunction with transrectal ultrasound-guided biopsy improves discrimination between clinically significant and insignificant prostate tumors and can spare patients unnecessary biopsies.
Patient age 70 years and above is an independent risk factor for perioperative morbidity, according to data from a national cohort.
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