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Delayed PCa Tx May Up Relapse

Patients whose radical prostatectomy was delayed more than 6 months had a nearly 2-fold increased risk of biochemical recurrence, a study found.

Study Zeroes in on Cause of Castration-Resistant Prostate Cancer

Some prostate cancer cells lack androgen receptor, and they proliferate faster than those that express androgen receptor under androgen-deficient conditions.

Ultrasound + MRI Improves High-Grade Prostate Cancer Detection

Well demarcated hypoechoic areas in suspicious regions on MRI identify men more likely to have Gleason 7 or higher prostate cancer found on biopsy.

Prostate Cancer Detection Improved With Combined Biopsy Targeting

In a study, visual registration in conjunction with image fusion resulted in the highest detection rate of clinically significant prostate cancer.

Genetic Differences in Prostate Cancer Pinpointed in Black Men

New findings could help explain why men of African ancestry are more likely than white men to die from prostate cancer.

Latest Prostate Cancer News

PCa Phenotype May Predict Response to Immune Checkpoint Blockade

PCa Phenotype May Predict Response to Immune Checkpoint Blockade

The MSI-H/dMMR phenotype in men with advanced PCa is associated with greater likelihood of a durable response to PD-1/PD-L1 inhibitors.

Suicide Risk Up More Than 4-fold for Cancer Patients

Suicide Risk Up More Than 4-fold for Cancer Patients

Standardized mortality ratio highest for cancers of lung, head and neck, testes, bladder, Hodgkin lymphoma.

Comorbidities Adversely Linked to Cancer Trial Participation

Comorbidities Adversely Linked to Cancer Trial Participation

Reduction in trial discussions, trial offers, trial participation seen with one or more comorbidities.

Younger Men With High-Grade PCa Less Likely to Die After RP Than RT

Younger Men With High-Grade PCa Less Likely to Die After RP Than RT

Patients younger than age 60 with Gleason 8-10 disease who had upfront surgery versus radiation therapy had a 63% lower risk of prostate cancer-specific mortality.

Early Post-RP Complications Directly Related to Age

Early Post-RP Complications Directly Related to Age

The risk of virtually all early postoperative complications increases with increasing patient age at radical prostatectomy for localized prostate cancer.

Toxicity From All-Grade AEs in Prostate Cancer Better Reflects QOL

Toxicity From All-Grade AEs in Prostate Cancer Better Reflects QOL

Patient-reported toxicity scores more associated with quality-of-life outcomes than clinician-reported scores.

New Surrogate Marker for ADT Evaluation Proposed

New Surrogate Marker for ADT Evaluation Proposed

Time interval free of biochemical failure may be a potential surrogate end point in the setting of androgen-deprivation therapy evaluation in men with prostate cancer.

Hypofractionated Radiotherapy May Benefit Patients With Localized Prostate Cancer

Hypofractionated Radiotherapy May Benefit Patients With Localized Prostate Cancer

A study suggests HIMRT may have some advantages over CIMRT for treating men with localized prostate cancer.

Overactive Bladder Linked to Prostate Cancer ADT

Overactive Bladder Linked to Prostate Cancer ADT

Compared with men receiving androgen deprivation therapy for prostate cancer, healthy men had a 98% decreased risk of overactive bladder, study finds.

Prostate Cancer Possibly Linked to Zinc Intake

Prostate Cancer Possibly Linked to Zinc Intake

In a Spanish study, the highest vs lowest tertile of dietary zinc intake was associated with a significant 66% increased relative risk of low-grade prostate cancer.

Abiraterone Outcomes Tied to NLR

Abiraterone Outcomes Tied to NLR

For example, men with a baseline NLR below 2.5, patients who received abiraterone had a significant 28% decreased risk of death.

Prostate Cancer Risk, Aggressiveness Tied to Socioeconomics

Prostate Cancer Risk, Aggressiveness Tied to Socioeconomics

Study of Canadian men looked at the association between prostate cancer and participants' socioeconomic position during childhood/adolescence and early and late adulthood.

Gleason 6 Prostate Cancer More Lethal in Black Men

Gleason 6 Prostate Cancer More Lethal in Black Men

Black men with Gleason 6 prostate cancer had a 1.5- to 2.0-fold increased risk of dying from their cancer compared with nonblack men, according to a new study.

Statins Plus ADT May Up Survival in Advanced Prostate Cancer

Statins Plus ADT May Up Survival in Advanced Prostate Cancer

Statin use by men receiving androgen deprivation therapy for advanced PCa was associated with decreased risk of overall and cancer-specific mortality.

Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Mean 2.9 years gained after 23 years of follow-up among men with localized prostate cancer

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