Prostate Cancer Patients Taking Statins Lived Longer
Study results strengthen researchers' arguments for further clinical trials evaluating the potential protective effect of statins.
HealthDay News — Statins may help lower mortality in patients with 4 common types of cancer, according to a study presented at the European Society of Cardiology's Frontiers in CardioVascular Biology 2016, held from July 8 to 10 in Florence, Italy.
Rahul Potluri, MD, a clinical lecturer at the Aston University School of Medicine in Birmingham, UK, and colleagues collected data on 929,552 patients listed in a clinical database from January 2000 to March 2013. Data on deaths was obtained from the UK Office for National Statistics. Among the patients in the study, 7,997 had lung cancer, 5,481 had breast cancer, 4,629 had prostate cancer, and 4,570 had bowel cancer.
After adjusting for factors including age, gender, ethnicity, and common causes of death, the researchers found that those taking statins lived longer than those who were not taking them. Patients taking statins appeared to have a 22% lower risk of dying from lung cancer, a 43% lower risk of dying from breast cancer, a 47% lower risk of dying from prostate cancer, and a 30% lower risk of dying from bowel cancer.
"The results of this study strengthen the argument for a clinical trial evaluating the possible protective effect of statins and other routinely used cardiovascular medications in patients with cancer. Whether it is statins and/or other cardiovascular drugs in combination that have an effect on mortality remains to be seen," Potluri said in a news release from the European Society of Cardiology. "Patients with cancer who are at high risk or have established cardiovascular disease should be given statins as per current guidelines. I don't think at the moment we can give statins for cancer per se. But this could change if there was a positive result in the clinical trial."
- Statins may be associated with reduced mortality in 4 common cancers [news release]. Sophia Antipolis, France: European Society of Cardiology. Published July 8, 2016. Accessed July 12, 2016.