Diagnosis & Disease Information

Sorafenib Outcomes Unaffected by Age

ISTANBUL—Age does not affect clinical outcomes in sorafenib-treated patients with advanced renal cell carcinoma (RCC), researchers announced here at the 31st congress of the European Society for Medical Oncology.

Risk of High BP Linked to Uric Acid, Study Says

Serum uric acid is strongly associated with hypertension in African Americans, suggesting that a simple blood test could predict risk, and that treatments to lower uric acid may be a novel way to reduce hypertension-related complications in this patient population, researchers say.

Renal Stones Linked to Migraine Drug

Topiramate (Topamax), a drug for epileptic seizures and migraine headaches, may cause systemic metabolic acidosis, lower urinary citrate excretion, and raise urinary pH if used long-term, data suggest. The side effects could significantly increase the likelihood of calcium phosphate stones, investigators warn.

Post-MI Mortality Risk Linked to GFR

CHICAGO—Using plasma fasting glucose level and glomerular filtration rate (GFR) in conjunction with the TIMI risk index improves 30-day mortality predictions following acute MI, data show.

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