Phosphate Binder Reduces FGF23 in CKD Patients
Patients with non-dialysis chronic kidney disease and iron deficiency anemia treated with ferric citrate experienced significant declines in FGF23 regardless of change in serum phosphorus.
Print Issue: December 01, 2017
‘Clinically Negligible’ Residual Kidney Function Still Beneficial
Even at very low levels, residual kidney function in hemodialysis patients clears uremic solutes.
Hypertension, Diabetes at Hemodialysis Initiation Increasing
From 1995 to 2015, the prevalence of hypertension and diabetes among patients starting hemodialysis increased from 67.9% to 87.6% and from 43.1% to 59.6%, respectively.
Post-Dialysis Survival Odds Better After CABG vs PCI
US veterans who underwent coronary artery bypass grafting versus percutaneous coronary intervention prior to starting dialysis had a 28% lower risk of death.
Resistant Hypertension Ups Risks of Cardiovascular Events, ESRD
Study of U.S. veterans found that patients with resistant hypertension had 23%, 31%, and 144% higher risk of myocardial infarction, stroke, and end-stage renal disease, respectively.
In-Hospital Mortality Linked to High, Low Phosphorus
Admission serum phosphorus levels below 2.5 and 4.9 mg/dL and above are associated with increased odds of dying in the hospital.
Second-Line Enzalutamide May Benefit Some mCRPC Patients
In a prospective study, mCRPC patients placed on enzalutamide after their disease progressed while on abiraterone therapy had a median radiographic progression-free survival of 8.1 months.
Active Surveillance Required After Prostate Cancer Focal Ablation
In a small but meaningful number of patients, Gleason pattern 4 disease missed by MRI and systematic biopsy is present outside the focal ablation zone.
Stone Risk Greater In Wetter Climates
New study may redefine the “stone belt” in the United States.
Evaluating Business Opportunities
Physicians need a good understanding of a potential partner, regardless of the business model being considered.
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