Diagnosis & Disease Information

Novel Agent Eases BPH-Related LUTS

PARIS—Ozarelix, an investigational agent, may be effective for selected men with lower urinary tract symptoms (LUTS) associated with BPH, phase II trial data suggest. The drug is a highly soluble luteinizing hormone releasing antagonist.

When Gender Is In Doubt, What Then?

Should children with disorders of sex development (DSD) —in which genitalia, chromosomes, or reproductive systems diverge from what is considered the norm for females or males—have reconstructive surgery before they are old enough to make their own decisions?

Donor Acceptance Criteria Widening

PRAGUE—New studies presented at the 13th Congress of the European Society for Organ Transplantation suggest that transplant surgeons can make more effective use of kidneys from deceased donors, even from donors at the outer limits of acceptance criteria.

Post-Biopsy Prophylaxis Caution Urged

SAN DIEGO—Urologists may need to re-examine the use of oral fluoroquinolones (FQ) as prophylaxis after transrectal ultrasound-guided (TRUS) biopsy of the prostate, according to study findings presented here at the annual meeting of the Infectious Diseases Society of America.

Type of Donor Death Matters

SAN FRANCISCO—Elderly recipients of expanded criteria donor (ECD) kidneys have worse outcomes if the organs come from non-beating heart donors rather than brain-dead donors, data suggest.

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