Nephrology News Archive
The investigational drug appeared safe and effective in 3 phase 2b trials.
Smokers had poorer response to cisplatin-based neoadjuvant chemotherapy, higher recurrence risk.
Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease.
Most medical school graduates leave school carrying debt. Here's what you can do to better manage your student loan debt.
Investigators report a significant 27% increased risk of Parkinson's disease among individuals aged 65 years and older but less than 75 years.
Patients younger than age 60 with Gleason 8-10 disease who had upfront surgery versus radiation therapy had a 63% lower risk of prostate cancer-specific mortality.
Lawsuits claim Johnson Johnson did not fully disclose safety risks of transvaginal mesh products.
Reduction in risk for range of critical outcomes greatest for daily dietary fiber intake of 25 to 29 g.
The risk of virtually all early postoperative complications increases with increasing patient age at radical prostatectomy for localized prostate cancer.
Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN
Health expenditure greater for person with 2 diseases simultaneously than for the diseases separately.
Fewer patients admitted to hospital for MI, cardiac arrest, stroke working at 3 years postevent
Women younger than 46 years undergoing surgical correction are especially at risk for depression.
Patient-reported toxicity scores more associated with quality-of-life outcomes than clinician-reported scores.
Considerable increase seen from 1997 through 2016, especially in direct-to-consumer advertising
In a small study, more than half of pediatric patients receiving cinacalcet experienced a 30% or greater decline in mean intact parathyroid hormone.
Time interval free of biochemical failure may be a potential surrogate end point in the setting of androgen-deprivation therapy evaluation in men with prostate cancer.
Socioeconomic inequalities are widening, but racial gap in cancer mortality narrowing slowly.
Reductions in BP from exercise comparable but not as great as from medications
Spironolactone improved cardiovascular outcomes in heart failure patients with chronic kidney disease, but increased their risk of hyperkalemia.
In a Japanese study, targeting high hemoglobin concentrations of 12.5-13.5 g/dL with erythropoiesis-stimulating agents resulted in longer graft survival.
A study suggests HIMRT may have some advantages over CIMRT for treating men with localized prostate cancer.
Compared with abstinence from alcohol, increased survival seen with moderate drinking
Rate of the primary outcome was similar for canagliflozin, glucagon-like peptide-1 agonist
Patients who underwent subtotal vs total parathyroidectomy had half the risk for cardiovascular events.
Compared with men receiving androgen deprivation therapy for prostate cancer, healthy men had a 98% decreased risk of overactive bladder, study finds.
Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury.
Survival benefit not seen with Stage 1 hypertension, only high-risk Stage 2 hypertension
In a small study of hemodialysis patients with secondary hyperparathyroidism, abdominal aortic calcification decreased more in patients who underwent parathyroidectomy than in those in a control group over 1 year.
Severe deficiency linked to increased prevalence of RHF in population with normal renal function
Cardiovascular risk increased with sulfonylureas and basal insulin versus newer classes of ADM
Cumulative proportional probability for AF events greatest for those in the highest quartile of salt intake
Achieving a work-life balance can be difficult as a clinician. Here are 6 tips to get it right.
Odds of CKD up with beverage pattern consisting of higher intake of sweetened soda, fruit drinks, water
Clinical practice guidelines presented for diagnosis, treatment, pediatric and pregnancy-linked VTE
Patients at risk include those with hypertension or certain genetic disorders and the elderly
Elevated serum potassium levels increased the risk for end-stage renal disease by approximately 30%, independent of decline in estimated glomerular filtration rate.
Patients who remain on loop diuretics after starting hemodialysis (HD) experience lower rates of hospitalization and intradialytic hypotension during the first year on HD, a study found.
Effect seen with aerobic endurance and high-intensity training but not resistance training
Mortality rate lower for habitually active patients and for those who started exercising after diagnosis
In general, ethical tension exists when a physician's obligation to promote a patient's best interests competes with the physician's obligation to respect the patient's autonomy.
As of last Saturday's enrollment deadline, 8.5 million people in 39 states had enrolled
Micronutrient supplements may be warranted for specific nutritional needs or deficiencies
A history of kidney stones is associated with an increased risk of papillary renal cell carcinoma and upper tract urothelial carcinoma, according to a large prospective study.
Fewer than a third of normal-weight adults, 8% of overweight adults are metabolically healthy
Experts suggest some simple ways medical practices can get patients to embrace healthy behaviors.
Barbers promoted follow-up with pharmacists, who prescribed blood pressure medication
17.1% of patients reported having experienced one or more events in previous year.
In a study of patients with chronic kidney disease, the technique for sequencing protein-coding genes yielded a genetic diagnosis in 9.3% of cases.
Oxycodone, heroin, and fentanyl ranked first in 2011, 2012-2015, 2016; cocaine ranked second or third
In a small study, sunitinib recipients who took royal jelly, a substance produced by worker honeybees for queen bees, were less likely to experience fatigue and anorexia than those who took placebo.
PD-related infection, mortality, fatigue are highest-ranked outcomes for patients, caregivers
16,100 CVD deaths attributable to higher sodium intake among those aged 25 to 69 in 2011
More female, black, and Hispanic matriculants seen after diversity accreditation standards implemented
Odds of burnout up with report of poor/marginal time for documentation, time spent on EHR at home
In a Spanish study, the highest vs lowest tertile of dietary zinc intake was associated with a significant 66% increased relative risk of low-grade prostate cancer.
Higher risk seen on Christmas Eve, particularly in older adults with diabetes, heart disease
Sex, high and low baseline potassium levels, and reduced renal function independently predict hyper- and hypokalemia in patients with heart failure.
For example, men with a baseline NLR below 2.5, patients who received abiraterone had a significant 28% decreased risk of death.
Fraud, health crimes, substance abuse exclusions increased 20% per year from 2007 to 2017
Study of Canadian men looked at the association between prostate cancer and participants' socioeconomic position during childhood/adolescence and early and late adulthood.
Updates include use of SGLT-2 inhibitors and GLP-1 receptor agonists for T2DM, CVD; endorsed by ACC
Proportion of patients with uncontrolled blood pressure varies by health system and clinical site
One-year mortality and admission lower for patients with follow-up care within 7 days of discharge
In a study, visual registration in conjunction with image fusion resulted in the highest detection rate of clinically significant prostate cancer.
For this study, the authors identified randomized controlled trials (RCTs) that compared SGLT2 inhibitors with placebo, no treatment, or another antidiabetic agent and reported on UTI outcome.
Lowest risk seen for adherent patients receiving high-intensity statin and/or ezetimibe regimen
Increase not linked to increase in subsequent RBC use, rehospitalization, mortality within 6 months
In a sea of job postings, candidates will flock to a certain type of ad. Here's what they're looking for.
Vitamin D receptor activators may not reduce cardiovascular risk in patients undergoing hemodialysis.
1. In this randomized clinical trial, patients on hemodialysis who received a vitamin D receptor activator (VDRA) did not have better cardiovascular health compared to those with placebo. 2. Patients receiving active vitamin D did not have reduced mortality. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with advanced chronic kidney disease (CKD) on hemodialysis 
Black men with Gleason 6 prostate cancer had a 1.5- to 2.0-fold increased risk of dying from their cancer compared with nonblack men, according to a new study.
Researchers found no significant difference in 30-day postoperative complications between patients who received neoadjuvant chemotherapy and those who did not.
In a small study of hemodialysis patients, substituting egg white for meat and fish in 3 meals per week resulted in a significant decrease in serum phosphate.
Researchers observed comparable long-term outcomes between patients with late- and early-onset lupus nephritis.
Statin use by men receiving androgen deprivation therapy for advanced PCa was associated with decreased risk of overall and cancer-specific mortality.
Median of 2 strips/day used by those taking agents not considered to be risk for causing hypoglycemia
New study finds a prevalence of benign pathologic findings after PN of 30.9%.
In a small study of patients on maintenance hemodialysis, phosphate binder use did not affect appetite, food intake, or malnutrition-inflammation score.
Researchers theorize that KPNA2 expression could be used in the future to stratify risk groups among patients with renal cell carcinoma (RCC).
In a study of nearly 300,000 South Koreans, individuals who tested positive for hepatitis B virus had an 11% higher risk of CKD.
Physician mothers report limited opportunities for advancement, financial inequalities, lack of support.
A study found that more than half of information breaches at health care organizations were due to internal issues such as sending emails to the wrong recipient.
Mean 2.9 years gained after 23 years of follow-up among men with localized prostate cancer
Poor vitamin K status is associated with inflammation and low areal bone mineral density (BMD) among patients with end-stage renal disease.
In a Japanese study, patients with the lowest serum phosphate levels at dialysis initiation had the greatest death risk.
When 121 regions were considered together, VHA care was better for 14 of 15 outcome measures
Rate has declined but remains higher in those with type 1 or 2 diabetes than in those without
In a small trial, patients receiving 300 U and 500 U of intravesical abobotulinumtoxin A experienced reductions in nocturia episodes at 12 and 24 weeks.
Sildenafil and tadalafil not approved to be sold over the counter and are being sold illegally.
After adjustment for confounders, vaccine linked to lower all-cause, cardiovascular death
A review article examines the challenges in pathologic staging and grade reporting for patients with renal cell carcinoma.
In a study, percutaneous tibial nerve stimulation reduced nocturia episodes by 0.8 on average.
Linagliptin added to usual care compared with placebo added to usual care resulted in a noninferior risk for a composite cardiovascular or renal outcome over a median 2.2 years.
41% are not at all familiar with personalized medicine; only 5% say they are very familiar.
Trial results do not support use of vitamin D receptor activators to prevent cardiovascular events in patients with end-stage renal disease and low intact parathyroid hormone levels.
Nocturia improved 43% in patients receiving oral desmopressin alone and 64.3% in those receiving desmopressin and an alpha-blocker.
Risk for statin-induced serious muscle injury 0.1 percent, newly diagnosed diabetes 0.2%
Study authors developed a Markov model with health states based on daily urinary incontinence episodes (UIEs) to compare the cost-effectiveness of onabotulinumtoxinA, implantable sacral nerve stimulation devices, percutaneous tibial nerve stimulation, anticholinergic medications, and mirabegron versus BSC for the management of refractory OAB.
Renal and Urology News Articles
- Younger Men With High-Grade PCa Less Likely to Die After RP Than RT
- Roxadustat Effective in Chronic Kidney Disease Patients With Anemia
- Novel Albuminuria Endpoints May Improve CKD Progression Trials
- Molidustat Promising for Renal Anemia
- Global Demand for Bladder Cancer Treatment Threatens Supply in 2019
- Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults
- Novel Albuminuria Endpoints May Improve CKD Progression Trials
- Younger Men With High-Grade PCa Less Likely to Die After RP Than RT
- Overactive Bladder Linked to Prostate Cancer ADT
- Second-Line Antidiabetic Meds May Impact Cardiovascular Risk
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NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)