Nephrology News Archive

Anemia Molidustat Promising for Renal Anemia

Molidustat Promising for Renal Anemia

The investigational drug appeared safe and effective in 3 phase 2b trials.

Bladder Cancer Smoking Associated With Worse Bladder Cancer Outcomes

Smoking Associated With Worse Bladder Cancer Outcomes

Smokers had poorer response to cisplatin-based neoadjuvant chemotherapy, higher recurrence risk.

Hypogonadism Testosterone Use Remains High Among Men With Coronary Artery Disease

Testosterone Use Remains High Among Men With Coronary Artery Disease

Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease.

Practice Management 3 Strategies to Manage Your Student Loan Debt After Medical School

3 Strategies to Manage Your Student Loan Debt After Medical School

Most medical school graduates leave school carrying debt. Here's what you can do to better manage your student loan debt.

Hyperuricemia Gout Linked to Elevated Risk of Parkinson's Disease

Gout Linked to Elevated Risk of Parkinson's Disease

Investigators report a significant 27% increased risk of Parkinson's disease among individuals aged 65 years and older but less than 75 years.

Prostate Cancer Younger Men With High-Grade PCa Less Likely to Die After RP Than RT

Younger Men With High-Grade PCa Less Likely to Die After RP Than RT

Patients younger than age 60 with Gleason 8-10 disease who had upfront surgery versus radiation therapy had a 63% lower risk of prostate cancer-specific mortality.

Urinary Incontinence Doctors Question State Lawsuits Over Pelvic Mesh Products

Doctors Question State Lawsuits Over Pelvic Mesh Products

Lawsuits claim Johnson Johnson did not fully disclose safety risks of transvaginal mesh products.

Cardiovascular Disease (CVD) High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

High Fiber Intake Tied to Lower Risk for Noncommunicable Disease

Reduction in risk for range of critical outcomes greatest for daily dietary fiber intake of 25 to 29 g.

Prostate Cancer Early Post-RP Complications Directly Related to Age

Early Post-RP Complications Directly Related to Age

The risk of virtually all early postoperative complications increases with increasing patient age at radical prostatectomy for localized prostate cancer.

Hypertension No Increased Fall Risk With Hypertension Tx in Older Women

No Increased Fall Risk With Hypertension Tx in Older Women

Lower incidence rate ratios found for women with treated controlled hypertension, treated uncontrolled HTN

Cardiovascular Disease (CVD) Costs Higher for Those With Comorbid Noncommunicable Diseases

Costs Higher for Those With Comorbid Noncommunicable Diseases

Health expenditure greater for person with 2 diseases simultaneously than for the diseases separately.

Cardiovascular Disease (CVD) Employment, Earning Losses Noted After Cardiovascular Events

Employment, Earning Losses Noted After Cardiovascular Events

Fewer patients admitted to hospital for MI, cardiac arrest, stroke working at 3 years postevent

Urinary Incontinence Reoperation for Mesh Complications May Up Depression Risk

Reoperation for Mesh Complications May Up Depression Risk

Women younger than 46 years undergoing surgical correction are especially at risk for depression.

Prostate Cancer Toxicity From All-Grade AEs in Prostate Cancer Better Reflects QOL

Toxicity From All-Grade AEs in Prostate Cancer Better Reflects QOL

Patient-reported toxicity scores more associated with quality-of-life outcomes than clinician-reported scores.

Hypogonadism Medical Marketing Has Increased in Past 20 Years

Medical Marketing Has Increased in Past 20 Years

Considerable increase seen from 1997 through 2016, especially in direct-to-consumer advertising

Secondary Hyperparathyroidism Cinacalcet Appears Safe, Effective for Children With SHPT

Cinacalcet Appears Safe, Effective for Children With SHPT

In a small study, more than half of pediatric patients receiving cinacalcet experienced a 30% or greater decline in mean intact parathyroid hormone.

Prostate Cancer New Surrogate Marker for ADT Evaluation Proposed

New Surrogate Marker for ADT Evaluation Proposed

Time interval free of biochemical failure may be a potential surrogate end point in the setting of androgen-deprivation therapy evaluation in men with prostate cancer.

Urology Cancer Death Rate in US Decreased Continuously From 1991 to 2016

Cancer Death Rate in US Decreased Continuously From 1991 to 2016

Socioeconomic inequalities are widening, but racial gap in cancer mortality narrowing slowly.

Hypertension Exercise Can Consistently Lower Blood Pressure

Exercise Can Consistently Lower Blood Pressure

Reductions in BP from exercise comparable but not as great as from medications

Hyperkalemia Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

Spironolactone Helps HF Patients With CKD, But Ups Hyperkalemia Risk

Spironolactone improved cardiovascular outcomes in heart failure patients with chronic kidney disease, but increased their risk of hyperkalemia.

Anemia Targeting High Hemoglobin in Post-Transplant Anemia Beneficial

Targeting High Hemoglobin in Post-Transplant Anemia Beneficial

In a Japanese study, targeting high hemoglobin concentrations of 12.5-13.5 g/dL with erythropoiesis-stimulating agents resulted in longer graft survival.

Prostate Cancer Hypofractionated Radiotherapy May Benefit Patients With Localized Prostate Cancer

Hypofractionated Radiotherapy May Benefit Patients With Localized Prostate Cancer

A study suggests HIMRT may have some advantages over CIMRT for treating men with localized prostate cancer.

Hypertension Moderate Drinking Not Harmful for Seniors With Heart Failure

Moderate Drinking Not Harmful for Seniors With Heart Failure

Compared with abstinence from alcohol, increased survival seen with moderate drinking

Diabetes No Increased Fracture Risk With Canagliflozin in Type 2 Diabetes

No Increased Fracture Risk With Canagliflozin in Type 2 Diabetes

Rate of the primary outcome was similar for canagliflozin, glucagon-like peptide-1 agonist

Secondary Hyperparathyroidism Cardiovascular Event Risk Higher With Total Parathyroidectomy

Cardiovascular Event Risk Higher With Total Parathyroidectomy

Patients who underwent subtotal vs total parathyroidectomy had half the risk for cardiovascular events.

Overactive Bladder (OAB) Overactive Bladder Linked to Prostate Cancer ADT

Overactive Bladder Linked to Prostate Cancer ADT

Compared with men receiving androgen deprivation therapy for prostate cancer, healthy men had a 98% decreased risk of overactive bladder, study finds.

Hypertension In-Hospital Morbidity, Mortality Up With Flu in Heart Failure

In-Hospital Morbidity, Mortality Up With Flu in Heart Failure

Higher incidence seen for in-hospital mortality, acute respiratory failure, acute kidney injury.

Hypertension New BP Treatment Cutoffs May Not Yield Survival Benefit

New BP Treatment Cutoffs May Not Yield Survival Benefit

Survival benefit not seen with Stage 1 hypertension, only high-risk Stage 2 hypertension

Secondary Hyperparathyroidism Parathyroidectomy for SHPT Reduces Aortic Calcification

Parathyroidectomy for SHPT Reduces Aortic Calcification

In a small study of hemodialysis patients with secondary hyperparathyroidism, abdominal aortic calcification decreased more in patients who underwent parathyroidectomy than in those in a control group over 1 year.

Nephrology Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults

Low Vitamin D Tied to Risk for Renal Hyperfiltration in Healthy Adults

Severe deficiency linked to increased prevalence of RHF in population with normal renal function

Diabetes Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

Second-Line Antidiabetic Meds May Impact Cardiovascular Risk

Cardiovascular risk increased with sulfonylureas and basal insulin versus newer classes of ADM

Nutrition High Sodium Intake Associated With New Atrial Fibrillation

High Sodium Intake Associated With New Atrial Fibrillation

Cumulative proportional probability for AF events greatest for those in the highest quartile of salt intake

Practice Management 6 Key Strategies to Achieve a Work-Life Balance

6 Key Strategies to Achieve a Work-Life Balance

Achieving a work-life balance can be difficult as a clinician. Here are 6 tips to get it right.

Chronic Kidney Disease (CKD) Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

Sugar-Sweetened Drinks Linked to Chronic Kidney Disease Risk

Odds of CKD up with beverage pattern consisting of higher intake of sweetened soda, fruit drinks, water

Urology ASH Develops Practice Guidelines for Venous Thromboembolism

ASH Develops Practice Guidelines for Venous Thromboembolism

Clinical practice guidelines presented for diagnosis, treatment, pediatric and pregnancy-linked VTE

Urology FDA: Fluoroquinolones Tied to Heart Vessel Ruptures, Tears

FDA: Fluoroquinolones Tied to Heart Vessel Ruptures, Tears

Patients at risk include those with hypertension or certain genetic disorders and the elderly

Hyperkalemia Hyperkalemia Increases Risk for Progression to ESRD

Hyperkalemia Increases Risk for Progression to ESRD

Elevated serum potassium levels increased the risk for end-stage renal disease by approximately 30%, independent of decline in estimated glomerular filtration rate.

Hemodialysis Hemodialysis Patients May Benefit by Staying on Loop Diuretics

Hemodialysis Patients May Benefit by Staying on Loop Diuretics

Patients who remain on loop diuretics after starting hemodialysis (HD) experience lower rates of hospitalization and intradialytic hypotension during the first year on HD, a study found.

Men's Health Update Endurance Exercise Tied to Anti-Aging at Cellular Level

Endurance Exercise Tied to Anti-Aging at Cellular Level

Effect seen with aerobic endurance and high-intensity training but not resistance training

Men's Health Update Exercise Linked to Reduced Mortality for Patients With Cancer

Exercise Linked to Reduced Mortality for Patients With Cancer

Mortality rate lower for habitually active patients and for those who started exercising after diagnosis

Ethical Issues in Medicine When Patients Refuse Recommended Treatments

When Patients Refuse Recommended Treatments

In general, ethical tension exists when a physician's obligation to promote a patient's best interests competes with the physician's obligation to respect the patient's autonomy.

Practice Management Affordable Care Act Sign-Ups Higher Than Expected

Affordable Care Act Sign-Ups Higher Than Expected

As of last Saturday's enrollment deadline, 8.5 million people in 39 states had enrolled

Nutrition Routine Supplements to Prevent Chronic Disease Not Advised

Routine Supplements to Prevent Chronic Disease Not Advised

Micronutrient supplements may be warranted for specific nutritional needs or deficiencies

Kidney Cancer Kidney Stones Up Kidney Cancer Risk

Kidney Stones Up Kidney Cancer Risk

A history of kidney stones is associated with an increased risk of papillary renal cell carcinoma and upper tract urothelial carcinoma, according to a large prospective study.

Home Prevalence of Metabolically Healthy Adults in US Very Low

Prevalence of Metabolically Healthy Adults in US Very Low

Fewer than a third of normal-weight adults, 8% of overweight adults are metabolically healthy

Practice Management Promoting Lifestyle Changes to Prevent Cancer

Promoting Lifestyle Changes to Prevent Cancer

Experts suggest some simple ways medical practices can get patients to embrace healthy behaviors.

Hypertension Barbershop Intervention Leads to Reduced BP in Black Men

Barbershop Intervention Leads to Reduced BP in Black Men

Barbers promoted follow-up with pharmacists, who prescribed blood pressure medication

Diabetes Fasting-Evoked Hypoglycemia in Diabetes Is Prevalent

Fasting-Evoked Hypoglycemia in Diabetes Is Prevalent

17.1% of patients reported having experienced one or more events in previous year.

Chronic Kidney Disease (CKD) Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

Exome Sequencing Zeroes in on Genetic Diagnoses in CKD

In a study of patients with chronic kidney disease, the technique for sequencing protein-coding genes yielded a genetic diagnosis in 9.3% of cases.

Benign Prostatic Hyperplasia (BPH) Seminal Vesicle Problems May Be a PAE Complication

Seminal Vesicle Problems May Be a PAE Complication

Men's Health Update CDC Identifies Drugs Frequently Involved in Drug Overdose Deaths

CDC Identifies Drugs Frequently Involved in Drug Overdose Deaths

Oxycodone, heroin, and fentanyl ranked first in 2011, 2012-2015, 2016; cocaine ranked second or third

Kidney Cancer Royal Jelly May Ease Adverse Effects of RCC Drug Therapy

Royal Jelly May Ease Adverse Effects of RCC Drug Therapy

In a small study, sunitinib recipients who took royal jelly, a substance produced by worker honeybees for queen bees, were less likely to experience fatigue and anorexia than those who took placebo.

Peritoneal Dialysis Outcomes of Importance ID'd for Peritoneal Dialysis Patients

Outcomes of Importance ID'd for Peritoneal Dialysis Patients

PD-related infection, mortality, fatigue are highest-ranked outcomes for patients, caregivers

Nutrition High Sodium May Contribute to CVD Deaths in Shandong, China

High Sodium May Contribute to CVD Deaths in Shandong, China

16,100 CVD deaths attributable to higher sodium intake among those aged 25 to 69 in 2011

Practice Management US Medical Schools See Increase in Diversity

US Medical Schools See Increase in Diversity

More female, black, and Hispanic matriculants seen after diversity accreditation standards implemented

Practice Management HIT-Related Stress Linked to Burnout Among Physicians

HIT-Related Stress Linked to Burnout Among Physicians

Odds of burnout up with report of poor/marginal time for documentation, time spent on EHR at home

Prostate Cancer Prostate Cancer Possibly Linked to Zinc Intake

Prostate Cancer Possibly Linked to Zinc Intake

In a Spanish study, the highest vs lowest tertile of dietary zinc intake was associated with a significant 66% increased relative risk of low-grade prostate cancer.

Cardiovascular Disease (CVD) Emotional Stress of Holidays Can Trigger Heart Attacks

Emotional Stress of Holidays Can Trigger Heart Attacks

Higher risk seen on Christmas Eve, particularly in older adults with diabetes, heart disease

Hyperkalemia Dyskalemia Common in Heart Failure

Dyskalemia Common in Heart Failure

Sex, high and low baseline potassium levels, and reduced renal function independently predict hyper- and hypokalemia in patients with heart failure.

Prostate Cancer Abiraterone Outcomes Tied to NLR

Abiraterone Outcomes Tied to NLR

For example, men with a baseline NLR below 2.5, patients who received abiraterone had a significant 28% decreased risk of death.

Practice Management Exclusion of Doctors From Public Health Insurance Up 2007 to 2017

Exclusion of Doctors From Public Health Insurance Up 2007 to 2017

Fraud, health crimes, substance abuse exclusions increased 20% per year from 2007 to 2017

Prostate Cancer Prostate Cancer Risk, Aggressiveness Tied to Socioeconomics

Prostate Cancer Risk, Aggressiveness Tied to Socioeconomics

Study of Canadian men looked at the association between prostate cancer and participants' socioeconomic position during childhood/adolescence and early and late adulthood.

Diabetes ADA 2019 Standards of Care Emphasize Patient-Centered Care

ADA 2019 Standards of Care Emphasize Patient-Centered Care

Updates include use of SGLT-2 inhibitors and GLP-1 receptor agonists for T2DM, CVD; endorsed by ACC

Hypertension EHR Data ID Differences in Hypertension Control Across Health Systems

EHR Data ID Differences in Hypertension Control Across Health Systems

Proportion of patients with uncontrolled blood pressure varies by health system and clinical site

Hypertension Follow-Up Within 7 Days of Heart Failure Discharge Beneficial

Follow-Up Within 7 Days of Heart Failure Discharge Beneficial

One-year mortality and admission lower for patients with follow-up care within 7 days of discharge

Prostate Cancer Prostate Cancer Detection Improved With Combined Biopsy Targeting

Prostate Cancer Detection Improved With Combined Biopsy Targeting

In a study, visual registration in conjunction with image fusion resulted in the highest detection rate of clinically significant prostate cancer.

Urinary Tract Infections (UTI) SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

SGLT2 Inhibitors and Urinary Tract Infections: What's the Link?

For this study, the authors identified randomized controlled trials (RCTs) that compared SGLT2 inhibitors with placebo, no treatment, or another antidiabetic agent and reported on UTI outcome.

Cardiovascular Disease (CVD) Adherence and Intensity of Lipid-Lowering Tx Influence CV Risk

Adherence and Intensity of Lipid-Lowering Tx Influence CV Risk

Lowest risk seen for adherent patients receiving high-intensity statin and/or ezetimibe regimen

Anemia 2010 to 2014 Saw Increase in Anemia After Hospitalization

2010 to 2014 Saw Increase in Anemia After Hospitalization

Increase not linked to increase in subsequent RBC use, rehospitalization, mortality within 6 months

Practice Management 5 Tips on Writing a Job Posting People Want to Apply to

5 Tips on Writing a Job Posting People Want to Apply to

In a sea of job postings, candidates will flock to a certain type of ad. Here's what they're looking for.

Trial Tracker

Vitamin D receptor activators may not reduce cardiovascular risk in patients undergoing hemodialysis.

1. In this randomized clinical trial, patients on hemodialysis who received a vitamin D receptor activator (VDRA) did not have better cardiovascular health compared to those with placebo. 2. Patients receiving active vitamin D did not have reduced mortality. Evidence Rating Level: 1 (Excellent) Study Rundown: Patients with advanced chronic kidney disease (CKD) on hemodialysis []

Prostate Cancer Gleason 6 Prostate Cancer More Lethal in Black Men

Gleason 6 Prostate Cancer More Lethal in Black Men

Black men with Gleason 6 prostate cancer had a 1.5- to 2.0-fold increased risk of dying from their cancer compared with nonblack men, according to a new study.

Bladder Cancer Post-Cystectomy Short-Term Complications Not Hiked by NAC

Post-Cystectomy Short-Term Complications Not Hiked by NAC

Researchers found no significant difference in 30-day postoperative complications between patients who received neoadjuvant chemotherapy and those who did not.

Hyperphosphatemia Replacing Meat With Egg White May Help Control Hyperphosphatemia

Replacing Meat With Egg White May Help Control Hyperphosphatemia

In a small study of hemodialysis patients, substituting egg white for meat and fish in 3 meals per week resulted in a significant decrease in serum phosphate.

Lupus Nephritis Similar Long-Term Outcomes in Early- vs Late-Onset Lupus Nephritis

Similar Long-Term Outcomes in Early- vs Late-Onset Lupus Nephritis

Researchers observed comparable long-term outcomes between patients with late- and early-onset lupus nephritis.

Prostate Cancer Statins Plus ADT May Up Survival in Advanced Prostate Cancer

Statins Plus ADT May Up Survival in Advanced Prostate Cancer

Statin use by men receiving androgen deprivation therapy for advanced PCa was associated with decreased risk of overall and cancer-specific mortality.

Diabetes Some With Type 2 Diabetes Inappropriately Monitoring Blood Glucose

Some With Type 2 Diabetes Inappropriately Monitoring Blood Glucose

Median of 2 strips/day used by those taking agents not considered to be risk for causing hypoglycemia

Kidney Cancer Benign Pathology After Partial Nephrectomy More Common Than Thought

Benign Pathology After Partial Nephrectomy More Common Than Thought

New study finds a prevalence of benign pathologic findings after PN of 30.9%.

Hyperphosphatemia Phosphate Binders Do Not Interfere With Nutrition

Phosphate Binders Do Not Interfere With Nutrition

In a small study of patients on maintenance hemodialysis, phosphate binder use did not affect appetite, food intake, or malnutrition-inflammation score.

Kidney Cancer Karyopherin a2 May Be Prognostic Indicator in Renal Cell Carcinoma

Karyopherin a2 May Be Prognostic Indicator in Renal Cell Carcinoma

Researchers theorize that KPNA2 expression could be used in the future to stratify risk groups among patients with renal cell carcinoma (RCC).

Chronic Kidney Disease (CKD) Chronic Kidney Disease Linked to Hepatitis B

Chronic Kidney Disease Linked to Hepatitis B

In a study of nearly 300,000 South Koreans, individuals who tested positive for hepatitis B virus had an 11% higher risk of CKD.

Practice Management Persistent Discrimination ID'd Among Physician Mothers

Persistent Discrimination ID'd Among Physician Mothers

Physician mothers report limited opportunities for advancement, financial inequalities, lack of support.

HIPAA Compliance The Threat From Within: Most Breaches Due to Employee Errors

The Threat From Within: Most Breaches Due to Employee Errors

A study found that more than half of information breaches at health care organizations were due to internal issues such as sending emails to the wrong recipient.

Prostate Cancer Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Radical Prostatectomy Has Lasting Benefit for Localized Cancer

Mean 2.9 years gained after 23 years of follow-up among men with localized prostate cancer

Transplantation Poor Vitamin K Status Linked to Low BMD, Increased Fracture Risk in ESRD

Poor Vitamin K Status Linked to Low BMD, Increased Fracture Risk in ESRD

Poor vitamin K status is associated with inflammation and low areal bone mineral density (BMD) among patients with end-stage renal disease.

Hyperphosphatemia Serum Phosphate at Dialysis Start Tied With Mortality

Serum Phosphate at Dialysis Start Tied With Mortality

In a Japanese study, patients with the lowest serum phosphate levels at dialysis initiation had the greatest death risk.

Urology Veterans Health Administration Hospitals Outperform Non-VHAs

Veterans Health Administration Hospitals Outperform Non-VHAs

When 121 regions were considered together, VHA care was better for 14 of 15 outcome measures

Hypertension Risk for Hospitalization for Heart Failure Greater With Diabetes

Risk for Hospitalization for Heart Failure Greater With Diabetes

Rate has declined but remains higher in those with type 1 or 2 diabetes than in those without

Overactive Bladder (OAB) OAB Symptoms Eased With Intravesical Botulinum Toxin

OAB Symptoms Eased With Intravesical Botulinum Toxin

In a small trial, patients receiving 300 U and 500 U of intravesical abobotulinumtoxin A experienced reductions in nocturia episodes at 12 and 24 weeks.

Erectile Dysfunction FDA: Some E-Cigarette Liquids Contain Erectile Dysfunction Meds

FDA: Some E-Cigarette Liquids Contain Erectile Dysfunction Meds

Sildenafil and tadalafil not approved to be sold over the counter and are being sold illegally.

Hypertension Flu Vaccine Linked to Reduced Risk for Death in Heart Failure

Flu Vaccine Linked to Reduced Risk for Death in Heart Failure

After adjustment for confounders, vaccine linked to lower all-cause, cardiovascular death

Kidney Cancer Changes in Renal Cell Carcinoma Pathologic Staging and Histologic Grading

Changes in Renal Cell Carcinoma Pathologic Staging and Histologic Grading

A review article examines the challenges in pathologic staging and grade reporting for patients with renal cell carcinoma.

Overactive Bladder (OAB) Nocturia, Overactive Bladder Improved With PTNS

Nocturia, Overactive Bladder Improved With PTNS

In a study, percutaneous tibial nerve stimulation reduced nocturia episodes by 0.8 on average.

Diabetes Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Noninferior CV Outcomes for Linagliptin in T2D With High CV, Renal Risk

Linagliptin added to usual care compared with placebo added to usual care resulted in a noninferior risk for a composite cardiovascular or renal outcome over a median 2.2 years.

Urology Many Americans Unaware of Promise of Personalized Medicine

Many Americans Unaware of Promise of Personalized Medicine

41% are not at all familiar with personalized medicine; only 5% say they are very familiar.

Secondary Hyperparathyroidism VDRAs Do Not Lower Cardiovascular Event Risk in HD

VDRAs Do Not Lower Cardiovascular Event Risk in HD

Trial results do not support use of vitamin D receptor activators to prevent cardiovascular events in patients with end-stage renal disease and low intact parathyroid hormone levels.

Benign Prostatic Hyperplasia (BPH) Desmopressin Effectively Treats Nocturia in BPH

Desmopressin Effectively Treats Nocturia in BPH

Nocturia improved 43% in patients receiving oral desmopressin alone and 64.3% in those receiving desmopressin and an alpha-blocker.

Cardiovascular Disease (CVD) AHA Scientific Statement: Low Risk of Side Effects for Statins

AHA Scientific Statement: Low Risk of Side Effects for Statins

Risk for statin-induced serious muscle injury 0.1 percent, newly diagnosed diabetes 0.2%

Overactive Bladder (OAB) Overactive Bladder Treatment: Which Is the Most Cost-Effective Option?

Overactive Bladder Treatment: Which Is the Most Cost-Effective Option?

Study authors developed a Markov model with health states based on daily urinary incontinence episodes (UIEs) to compare the cost-effectiveness of onabotulinumtoxinA, implantable sacral nerve stimulation devices, percutaneous tibial nerve stimulation, anticholinergic medications, and mirabegron versus BSC for the management of refractory OAB.

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