Hyponatremia After Urologic Surgery Predicts Higher Mortality
In a study, the condition developed in 16.5% of patients who had bladder, prostate, ureter, or kidney surgery.
CHICAGO—Hyponatremia that develops following urologic surgery is associated with worse survival and long-term renal outcome, researchers concluded in a poster presentation at the American Society of Nephrology's 2016 Kidney Week meeting.
Sehoon Park, MD, of Seoul National University Hospital in Korea, and colleagues reviewed the medical records of 9449 bladder, prostate, ureter, and kidney surgery cases. Of these, hyponatremia—serum sodium level below 135 mEq/L—developed within 7 days of surgery in 1562 (16.5%). Most hyponatremia developed in patients with high-risk perioperative characteristics.
In adjusted analyses, postoperative hyponatremia was associated with a significant 46% increased risk of death from any cause and a significant 31% increased risk of dialysis initiation or a new diagnosis of stage 5 chronic kidney disease (estimated glomerular filtration rate less than 15 mL/min/1.73 m2).
- Park S et al. Postoperative hyponatremia in urologic surgery is associated with poor survival and long-term renal outcome. Poster presented at the 2016 Kidney Week meeting in Chicago, Nov. 15-20. Poster TH-PO491.