Kidney Cancer

Lymphadenectomy Offers No Survival Benefit in Nonmetastatic RCC

Lymphadenectomy Offers No Survival Benefit in Nonmetastatic RCC

By

Lymph node dissection did not influence overall survival even among patients with clinically positive nodal disease.

Front-Line Combo Found Superior for Advanced RCC

Front-Line Combo Found Superior for Advanced RCC

By

Avelumab plus axitinib is associated with longer progression-free survival compared with sunitinib as first-line therapy in patients with advanced renal cell carcinoma.

ASTRO: Stereotactic Ablative RT OK for RCC in Solitary Kidneys

ASTRO: Stereotactic Ablative RT OK for RCC in Solitary Kidneys

Local control, cancer-specific survival at 2 years similar for patients with solitary, bilateral kidneys

Later-Stage RCC at Diagnosis Less Likely in Blacks

Later-Stage RCC at Diagnosis Less Likely in Blacks

By

At the time of diagnosis of renal cell carcinoma, blacks had 33% lower odds of regional disease compared with whites, a new study found.

ESRD Risk Following Kidney Cancer Surgery Characterized

ESRD Risk Following Kidney Cancer Surgery Characterized

By

Australian study shows that end-stage renal disease develops in 1.7% of patients with 3 years of undergoing nephrectomy for kidney cancer.

Renal Biopsy Rarely Leads to Upstaging to Perinephric Fat Involvement

Renal Biopsy Rarely Leads to Upstaging to Perinephric Fat Involvement

By

Study of patients with clinical T1a renal cell carcinoma shows that those who undergo renal mass biopsy have only a 1.2% rate of upstaging to pT3a perinephric fat involvement.

Radical, Partial Nephrectomy Do Not Differ in Survival Outcomes

Radical, Partial Nephrectomy Do Not Differ in Survival Outcomes

By

Propensity score-matched analysis shows that radical and partial nephrectomy for cT1 renal cell carcinoma are associated with similar cancer-specific and all-cause mortality, a study found.

Risk Factors for Bone Metastases at RCC Diagnosis Identified

Risk Factors for Bone Metastases at RCC Diagnosis Identified

By

Older age, male sex, and higher T stage are associated with an increased risk of having bone metastases at initial diagnosis of renal cell carcinoma, study finds.

Partial Nephrectomy for Small Renal Tumors Offers Survival Edge

Partial Nephrectomy for Small Renal Tumors Offers Survival Edge

By

Partial vs radical nephrectomy is associated with an overall survival advantage among patients with RCC tumors 4 cm or smaller and many patients with larger tumors.

NLR Predicts Survival After Cytoreductive Nephrectomy+Thrombectomy

NLR Predicts Survival After Cytoreductive Nephrectomy+Thrombectomy

By

A neutrophil-lymphocyte ratio below 4 is associated with significantly longer survival among patients with non-poor-risk metastatic renal cell carcinoma.

Diabetes Population Has Higher Incidences of Bladder, Kidney Cancer

Diabetes Population Has Higher Incidences of Bladder, Kidney Cancer

By

Finnish study of individuals with type 2 diabetes reveals a 17% and 42% higher incidence of bladder and kidney cancer, respectively, compared with the general population.

High BMI at Start of Advanced RCC Systemic Therapy Ups Survival Odds

High BMI at Start of Advanced RCC Systemic Therapy Ups Survival Odds

By

In a German study of patients starting first-line systemic therapy for advanced renal cell carcinoma, patients with a low BMI were twice as likely to die as those with a high BMI.

New Study Supports Recent AUA Guidelines for Small Renal Masses

New Study Supports Recent AUA Guidelines for Small Renal Masses

By

Prospective study at Johns Hopkins shows excellent oncologic outcomes and preserved mental quality of life for all patients regardless of management strategy, with worse renal function after radical nephrectomy.

Nonsurgical treatment of small tumor renal cancer may be as effective as radical nephrectomy but with fewer complications

1. Rates of renal insufficiency were highest in patients receiving renal nephrectomy, compared to less invasive treatments. 2. Survival rates for renal nephrectomy and partial nephrectomy were very similar, suggesting little difference in efficacy between these treatments. Evidence Rating Level: 2 (Good) Study Rundown: Renal stage carcinoma (RCC) has relatively low mortality rates with respect []

Alternative Sunitinib Regimen for Advanced RCC Proposed

Alternative Sunitinib Regimen for Advanced RCC Proposed

By

A "weekday-on and weekend-off regimen" improves relative dose intensity compared with the conventional regimen, a study found.

Off-Clamp Partial Nephrectomy Better for Preserving Renal Function

Off-Clamp Partial Nephrectomy Better for Preserving Renal Function

By

In a study, the off-clamp approach to partial nephrectomy also was associated with lower risk for acute kidney injury.

Biomarkers May Predict TKI Response in Metastatic RCC

Biomarkers May Predict TKI Response in Metastatic RCC

Circulating blood biomarkers related to angiogenesis may help clinicians predict who will have a robust response to sunitinib.

Certain Renal Cancer Subtypes Linked to Obesity

Certain Renal Cancer Subtypes Linked to Obesity

By

Obesity is associated with an increased likelihood of clear cell and possibly chromophobe renal cell carcinoma.

Renal Tumor Size Influences Its Aggressiveness

Renal Tumor Size Influences Its Aggressiveness

By

The likelihood of aggressive kidney tumor histology increased along with tumor size, a new study found.

Rise in Localized High-Risk RCC Reported

Rise in Localized High-Risk RCC Reported

By

Over a 25-year period, the proportion of patients with high-risk clinical T1 tumors increased by nearly 20% and clinical tumor size decreased from 8.4 to 6.2 cm, an Italian study found.

Robotic Partial Nephrectomy Mostly Superior to Other Surgeries

Robotic Partial Nephrectomy Mostly Superior to Other Surgeries

By

Robotic PN was associated with significantly lower rates of complications, cancer recurrence, and mortality compared with open and laparoscopic PN.

High Body Mass Index May Predict Survival Outcomes in RCC

High Body Mass Index May Predict Survival Outcomes in RCC

The association between obesity, age, and renal cell carcinoma prognosis requires additional investigation.

New Findings Support Ablation for Small Renal Tumors

New Findings Support Ablation for Small Renal Tumors

By

Percutaneous ablation offers cancer-related outcomes similar to those of radical nephrectomy but with a lower likelihood of long-term renal insufficiency and complications.

Cancer Development Linked to Increased Diabetes Risk

Cancer Development Linked to Increased Diabetes Risk

Increased risk of subsequent diabetes independent of traditional diabetes risk factors.

Robotics Involved in Most Urologic Cancer Surgeries

Robotics Involved in Most Urologic Cancer Surgeries

By

In 2015, 69% of surgeries for prostate, bladder, and kidney cancer were performed with robotic assistance, a new meta-analysis shows.

Sunitinib Alone or After Surgery for mRCC Offers Similar Outcomes

Sunitinib Alone or After Surgery for mRCC Offers Similar Outcomes

By

New findings from the CARMENA trial contradict previous research showing better survival from cytoreductive nephrectomy followed by targeted therapy.

Readmission Risk Factors for Radical Nephrectomy Patients Identified

Readmission Risk Factors for Radical Nephrectomy Patients Identified

By

Race, procedure and insurance type, sex, surgeon volume, and hospital size influence the risk of readmission among patients undergoing radical nephrectomy, study finds.

Partial vs Radical Nephrectomy Lowers Elderly Patient Mortality Risk

Partial vs Radical Nephrectomy Lowers Elderly Patient Mortality Risk

By

Study shows that partial nephrectomy for small renal tumors is associated with lower risk of cancer-specific and other-cause mortality in patients aged 75 years and older.

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

Smoking Ups Bladder Cancer Risk, Lowers Prostate Cancer Risk

By

Men and women who smoke are at 2.3-fold and 2.7-fold increased risk of bladder cancer compared with non-smokers.

Odds of Prescribing Drugs Up With Doc Receipt of Payments

Odds of Prescribing Drugs Up With Doc Receipt of Payments

Doctors who receive general payment for cancer drug more likely to prescribe drug marketed by company.

Sign Up for Free e-newsletters