October 2017 Issue of Renal And Urology News

October 2017 Issue of Renal And Urology News

Renal & Urology News Sept-Oct 2017 Issue

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Nephrology Cover Articles

CKD May Be a Risk Factor for NMIBC Recurrence, Progression

Stage G3b-5 chronic kidney disease independently predicted a nearly 2-fold increased risk recurrence and 3-fold increased risk of progression following transurethral resection.

Metoprolol Increases Uric Acid, Risk of Gout

In a study of African Americans with hypertension-related CKD, metoprolol, but neither ramipril nor amlodipine, increased serum uric acid levels.

AKI After Computed Tomography Not Tied to Contrast

AKI occurred with similar frequency among patients who did and did not receive contrast medium.

Pruritus in Hemodialysis Patients Underestimated, Undertreated

Among hemodialysis patients always or nearly always bothered by itchy skin, 17% did not report their symptoms to a health care provider and 18% used ...

Urology Cover Articles

Early NLR Changes Predict mRCC Immunotherapy Outcomes

Rises and decreases in neutrophil-to-lymphocyte ratio at 6 weeks after treatment with anti-PD-1/PD-L1 immune checkpoint blockade is associated with progression-free and overall survival.

Immunotherapy Superior to Sunitinib for Front-Line mRCC Treatment

Checkpoint inhibitor combination of nivolumab plus ipilimumab improved progression-free and overall survival compared with sunitinib.

News in Brief

Low-Dose Aspirin May Lower Preeclampsia Risk

Women at high risk for preeclampsia who took 150 mg of aspirin daily during pregnancy had 62% lower odds of developing the condition.

Drug Approved for Complicated Urinary Tract Infections

Vabomere, which combines meropenem and vaborbactam, demonstrated superior efficacy to piperacillin/tazobactam.

Methylene Blue Improves Onabotulinum Toxin A Injection Technique

Methylene blue aids observation of the procedure and assessment of drug distribution.

Men With PCa Most Likely to Die From Other Causes

Non-metastatic prostate cancer patients are more likely to die from causes other than the disease.

Serum Uromodulin May Predict CKD Development

Uromodulin may be a novel predictive serum biomarker.

Practice Management

Training Staff in HIPAA Regulations

Physician organizations need to do a better job training staff in safeguarding protected health information and complying with HIPAA in other ways.

Evaluating Practice Options in the Shifting Health Care Landscape

Partnering with another organization may provide multiple benefits, including support for participating in new value-based agreements, infrastructure to comply with regulations and access to the ...

General News

Novel Parathyroidectomy Procedure May Result in Durably Low PTH

Typically, about 2% to 20% of SHPT patients experience recurrence or persistence after conventional parathyroidectomy procedures, likely due to residual parathyroid tissue.

Prostate Atrophy, Inflammation Associated With Lower PCa Risk

Both findings on biopsy also predict a lower odds of high-grade cancer.

Mortality Up for ER Patients Discharged With AKI

Higher mortality was seen in association with an emergency department discharge with acute kidney injury vs no acute kidney injury.

Olfactory Deficits, Malnutrition Markers Linked in CKD, ESRD Patients

Pilot study suggests intranasal theophylline may be worth further investigation as a treatment.

Timing of PSA Nadir Post-RP Predicts Biochemical Recurrence Risk

A detectable PSA nadir combined with shorter time to nadir after prostate cancer surgery is associated with a higher risk of biochemical recurrence.

Blacks Less Likely to Undergo Definitive Prostate Cancer Therapy

Study of men with intermediate- or high-risk prostate cancer finds facility-level racial disparity in use of definitive treatment.

Not All High-Risk Prostate Cancers Are the Same

Men with 1 high-risk factor experience better outcomes following treatment than those with 2 or 3 high-risk factors, study finds.

Cancer Patient Self-Reporting Reliable and Feasible, Studies Show

Prostate cancer patients accurately report their comorbidities, and participants in cancer clinical trials report more adverse events than trial investigators.

Study: Cystectomy Complication Rate Not Improving

Researchers find no significant change in overall complication rate from 2010 to 2015, but hospital length of stay and need for transfusion have declined.

Researchers: Iron-based Binders Best for Hyperphosphatemia

Of 7 phosphate binders, iron-based agents were optimal when efficacy and safety are considered.

Cancer Drug Slows ADPKD Cyst Growth, Study Finds

Bosutinib treatment was associated with a 66% decrease in the annual rate of kidney enlargement.

Urologist Ownership of IMRT Linked to Its Greater Use for PCa

Patients are more likely to receive intensity-modulated radiation therapy if they are managed by urology practices with an ownership interest in the modality, study finds.

Study Finds No Link Between Marijuana Use and Kidney Function

No significant association found between marijuana use and change in estimated glomerular filtration rate or development of albuminuria.

Liraglutide Linked With Lower Diabetic Kidney Disease Risk

Liraglutide-treated patients were 22% less likely than placebo recipients to experience a composite outcome of renal events.

Prostate Cancer Screening Saves Lives, New Analysis Shows

A European trial found a survival benefit from PCa screening and a US trial did not, but a new analysis finds that both trials provide ...

Arteriovenous Fistulas Not Always the Best Option

Despite low infection rates, AVFs have a high risk of maturation failure and abandonment.

Upfront Cabozantinib for Advanced RCC Improves Outcomes

Cabozantinib reduced the risk of disease progression or death compared with sunitinib among patients with previously untreated advanced renal cell carcinoma.

Intensive BP Control May Reduce Death Risk in CKD Patients

Targeting and treating systolic blood pressure to a lower range was associated with a 14% decreased risk of death, meta-analysis shows.

Proximal PSA Predicts Prostate Cancer Metastasis Risk

PSA levels of 10 ng/mL or higher in men who have biochemically recurrent PCa after radical prostatectomy and a PSADT less than 12 months are ...

Chronic Kidney Disease Raises Tinnitus Risk

Tinnitus is 3-fold more likely to develop in patients with versus without chronic kidney disease, new study shows.

Prostate Cancer Active Surveillance Use Low, But Increasing

Use of active surveillance for very low-risk prostate cancer rose from 11.6% of patients in 2010 to 27.3% in 2013, study finds.

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