May 2017 Issue of Renal And Urology News

May 2017 Issue of Renal And Urology News

Renal & Urology News May-June 2017 Issue

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Nephrology Cover Articles

Topically Applied Drug May Improve Hemodialysis Fistula Survival

In a study, vonapanitase did not improve primary patency compared with placebo, but did improve secondary patency and fistula use for hemodialysis.

Voclosporin Shows Promise as Lupus Nephritis Treatment

In a phase 2b trial, around half of patients taking the novel calcineurin inhibitor at a dose of 23.7 mg twice daily achieved complete remission ...

Obesity Ups Diabetes Risk Among Living Kidney Donors

The adjusted 5-year risk of insulin use following donation is 5 times higher among obese vs normal weight donors.

Higher Uric Acid Levels Up Nephrolithiasis Risk

Nephrolithiasis developed in 18,777 healthy men during 1,184,654 person-years of follow-up.

Urology Cover Articles

Prostatic Urethral Lift an Effective Option for Obstructed Patients

In a study, 86% of prostatic urethral lift patients experienced symptom relief in the first month.

Sipuleucel-T Survival Benefit Greater in Blacks

Median overall survival was 9.3 months longer for black versus white patients with metastatic castration-resistant prostate cancer.

AUA Releases Updated Renal Mass Guidelines

The document spells out in greater detail the criteria for radical and partial nephrectomy and for placing patients on active surveillance.

News in Brief

Stenting May Improve Transplant Renal Artery Stenosis Outcomes

Angioplasty plus stenting is associated with less residual stenosis and a lower restenosis rate compared with angioplasty alone.

Cinacalcet May Lower Death Risk in Dialysis Subgroups

Researchers found lower all-cause mortality for cinacalcet-treated patients concomitantly treated with vitamin D and phosphate binders, for example.

Chronic Prostatitis Has Adverse Effects on Sperm

CBP was associated with a reduction in sperm concentration, sperm vitality, sperm total and progressive motility.

Coffee Consumption Does Not Worsen ADPKD

Coffee drinkers did not have a statistically significant difference in kidney size or estimated glomerular filtration rate compared with those who did not drink coffee.

HIV-Infected Living Kidney Donors Have Low ESRD Risk

HIV-positive individuals with well-controlled disease and no comorbidities have a low risk of ESRD following living kidney donation.

'Real-World' Data Support PUL Use for LUTS

PUL involves placement of small permanent metallic implants into the prostate that lift the lateral lobes away from the urethra and remove obstruction.

Outpatient IPP Surgery on the Rise

The Southeast region performed the highest proportion of outpatient surgeries (46.7%), followed by the Midwest, Southwest, West, and Northeast.

Positive Lymph Node Prostate Cancer Care Patterns Characterized

63% of patients were managed initially with observation.

Editor's Letter

What Not to Eat After Nephrectomy

Both urologists and nephrologists provide follow-up and continuity of care to patients after cancer nephrectomy.

Meetings Calendar

Most US Gout Sufferers Not Taking Urate-Lowering Drugs

Gout is uncontrolled in the majority of individuals with the condition, data show.

Hemodialysis Patient Hospitalization Rates Declining

Study documents an upswing in emergency department visits and observation stays.

Sudden Cardiac Death Rate Remains High Among Hemodialysis Patients

Among hemodialysis patients, sudden cardiac death accounted for 12% more cardiovascular-related mortalities in 2013 than in 2009.

Antibiotic Combo Found to Reduce Post-Transplant UTI Rate

Post-transplant UTI rates were lower when cephalexin was added to SMX-TMP than when SMX-TMP was used alone (7.5% vs 25.8%), study finds.

Diabetes Increases Post-Transplant Mortality Risk

In a study, diabetes in both the donor and recipient was associated with triple the risk of death at 5 years post-transplant compared with the ...

Opioid Use Linked to Worse Outcomes in Kidney Transplant Patients

Highest level of opioid use in the year prior to transplantation was associated with a 45% and 28% increased risk of death and graft loss, ...

Cholesterol Linked to High-Grade Prostate Cancer

Each 10 mg/dL increase in total cholesterol is associated with a significant 23% greater odds of high-grade prostate cancer.

Nomogram Developed to Predict Ureteral Stone Passage

Likelihood of stone passage in patients on medical expulsive therapy is based on variables such as stone size and location and white blood cell count.

New Nomogram Improves Post-RP Metastasis Predictions

Nomogram based on a cohort of men with high-risk prostate cancer is more accurate than the CAPRA and MSKCC nomograms, researchers report.

Continent Diversion After Bladder Cancer Surgery on the Decline

Use of continent diversion procedures peaked in 2008, and has been decreasing since.

VTE Risk Continues Long After Bladder Cancer Surgery

The cumulative incidence of venous thromboembolism following radical cystectomy was nearly 6.7% over 10 years.

Water Vapor Ablation Eases BPH-Related Urinary Retention

In a study, 81.1% of men were able to void after an average of 28 days after treatment.

Low Testosterone Increases Women's Urinary Incontinence Risk

Lowest quartile of serum testosterone is associated with 48% and 65% increased odds of stress and mixed urinary incontinence, respectively.

Neoadjuvant Chemo Benefits Some Variant MIBC Patients

Researchers find prolonged survival among patients with neuroendocrine muscle-invasive bladder cancer.

Practice Management

How Medical Practices Can Improve Collection Rates

Medical groups may need to address such issues as claims denials and failure to obtain prior authorization.

General News

Living Kidney Donor Graft Survival Improving

Five-year graft survival rates among recipients of kidneys from living donors increased from 76.6% in 1985-1894 to 85.4% in 2009-2015.

Kidney Donor-Recipient CMV Matching Is a Promising Strategy

Researchers report that matching deceased kidney donors and kidney recipients by cytomegalovirus serostatus optimizes high- and low-risk profiles.

Accepting High-Risk Kidneys Is Better Than Waiting

High-KDPI kidneys can improve the likelihood of a functioning graft compared with waiting for a superior kidney.

Post-Transplant Infections, Cancer Do Not Up Mortality

Opportunistic viral and fungal infections or malignancies develop in 34% of kidney transplant recipients, but these complications do not affect patient or graft survival.

Gout Risk Is Lower Among Healthier Eaters

A DASH-style diet is associated with a reduced risk of gout, whereas a Western diet is associated with a higher risk.

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