January 2009 Issue of Renal And Urology News

January 2009 Issue of Renal And Urology News

January 2009

Cover Articles

Lithotripsy Use Declining?

A shift from shock-wave lithotripsy toward flexible ureteroscopy is changing the landscape of stone disease treatment, said Mihir M. Desai, MD, during the Cleveland Clinic's ...

Testosterone Therapy After RP May Work

TORONTO—Testosterone replacement therapy (TRT) may be effective in improving testosterone levels in hypogonadal men following radical prostatectomy (RP)

CKD Risk Is Higher in Stone Formers

PHILADELPHIA—Kidney stones may damage the kidneys and lead to CKD, according to a new study.

News in Brief

Ethanol May Be a BPH Option

Transurethral ethanol injection may be a treatment options for some men with benign prostatic hyperplasia (BPH), long-term study data suggest.

Sleep Posture, Stones Linked

Sleep posture may play a causative role in promoting renal stones, Iranian investigators reported in the Scandinavian Journal of Urology and Nephrology (2008; 42:551-554).

Cranberry vs. Antibiotic for UTI Prevention

Cranberry extract may be a suitable alternative to antibiotics for preventing recurrent UTIs in older women, British researchers concluded in The Journal of Antimicrobial Chemotherapy ...

Statins May Improve AKI Recovery After Surgery

Statin use is associated with improved recovery from acute kidney injury (AKI) following major surgery, according to a study published in Nephrology Dialysis Transplantation (2008;23:3867-3873).

Bad Vision Common Elderly HD Patients

Elderly hemodialysis (HD) patients have a high rate of visual impairment, data suggest.


GFR Threshold for CKD Challenged

Agreement on what are normal values in medicine often is a prerequisite to the development of clinical guidelines. But what happens if guidelines are based ...

World Literature Review

Chemokine Is Identified as a Marker for Acute Rejection

Measuring levels of the chemokine fractalkine in the urine is a noninvasive way to detect acute rejection of renal allografts, according to Chinese investigators. High ...

Adjuvant Radiotherapy Found Not to Improve PCa Survival

Adjuvant radiotherapy following radical prostatectomy (RP) for prostate cancer has no effect on overall and cancer-specific survival, a Canadian team reports.

Two Modes of Acupuncture May Work for Hot Flushes

Two modes of acupuncture appear to decrease the number and distress of hot flushes in men receiving castrational treatment for prostate cancer, according to a ...

FDA News

TRT System Now Indicated for AKI Patients

FlowMedica, Inc., of Fremont, Calif., announced that it has received clearance for a new labeling indication for its Benephit Infusion Systems, which can now facilitate ...

Trial for Fluid Replacement System and CIN Prevention

PLC Medical Systems, Inc., of Franklin, Mass., has received full approval for a U.S. pivotal trial to study the effectiveness of its RenalGuard System and ...

NDA Accepted for Six-Month Prostate Cancer Treatment

The New Drug Application (NDA) by Watson Pharmaceuticals, Inc., for a six-month formulation of Trelstar (triptorelin pamoate) has been accepted for filing.

New Data Required on Drug for Diabetic Foot Infections

Johnson & Johnson Pharmaceutical Research & Development, LLC, has received a Complete Response letter regarding its New Drug Application for ceftobiprole medocaril to treat complicated ...

Analgesic for Acute Pain Okayed

The FDA has approved tapentadol hydrochloride, an immediate-release oral tablet in doses of 50, 75, or 100 mg for the relief of moderate-to-severe acute pain.

Legal Issues

Unexpected Penectomy Lands Urologist in Court

Physicians and hospitals typically require patients to sign a boilerplate consent form before surgery. These forms usually specify that in the event of an emergency ...

Malpractice News

Color Coding Cuts Medication Errors in OR

Using color-coded, peel-off labels to match medication vials and delivery syringes can sharply boost accuracy and efficiency during surgery, a team of anesthesiologists at Penn ...

Survey: Few Premiums Increased in 2008

Most physicians saw their malpractice insurance costs stabilize last year, and more than 40% actually paid less for their coverage, a national survey has found.

Mediation Decreases Malpractice Case Load

Mandatory mediation of medical malpractice cases seems to be speeding the judicial process in Madison County, Ill.

Renal Nutrition Update

If Transplant Candidates' Diets Fail

Patients who need to lose weight to have a renal transplant have several bariatric options.

General News

No. 1 Post-Transplant Infection: UTIs

WASHINGTON, D.C.—UTIs continue to be the most common infections following kidney transplantation, with female gender and duration of urinary catheterization among the strongest risk factors.

Statins Cut Infection Risk in Transplant Patients

WASHINGTON, D.C.—Statin therapy may help solid-organ transplant (SOT) patients reduce their risk of death from bloodstream infections (BSIs), according to researchers.

Oral Insulin Spray Showing Promise

A form of needle-free insulin that is absorbed through the lining of the mouth may offer some diabetic patients a convenient new way to receive ...

Aliskiren Offers Better BP Control

ROME—Aliskiren, an oral direct renin inhibitor, lowers BP more effectively than hydrochlorothiazide as monotherapy or with add-on amlodipine in obese patients with hypertension, according to ...

Hypomagnesemia Is Often Neglected

CLEVELAND—Although magnesium is abundant, "it is the most neglected nutrient cation," said Zalman S. Agus, MD, at the Cleveland Clinic's Nephrology Update 2008.

Environmental Chemicals Bad for Sperm

SAN FRANCISCO—Three chemicals that are used in manufacturing and wind up in the environment may significantly decrease sperm motility and viability, new findings suggest.

Laser Therapy May Improve Fertility

SAN FRANCISCO—Low-level laser therapy (LLLT) may perk up sperm and improve fertility rates, according to a newly released study.

AKI May Raise ESRD Risk

Acute kidney injury (AKI) caused by trauma, illness, or surgery may predispose patients to end-stage renal disease (ESRD), new findings suggest.

Popular Drugs Found to Decrease PSA Levels

Two of the most common classes of medication — statins and nonsteroidal anti-inflammatory drugs (NSAIDs) — may compromise cancer screenings by lowering serum prostate-specific antigen ...

Antioxidants Fail to Prevent Cancer

Antioxidant supplementation has no effect on the risk of prostate and certain other cancers, according to two large longitudinal trials, leading one of them to ...

Drugs Comparable for Adolescent Lupus Nephritis

SAN FRANCISCO—Lupus nephritis (LN) in adolescents responds similarly to mycophenolate mofetil (MMF) and IV cyclophosphamide, according to data reported at the American College of Rheumatology ...

TURP Is Inferior for Prostate Cancer Detection

Transurethral resection of the prostate (TURP) is effective for treating benign prostatic obstruction, but it is not reliable for detecting cancer, data show.

Avoiding Urologic Surgery Infections

Periprocedural infections are an important health care concern. Surgical-site infections occur after 5% of clean extra-abdominal procedures and are even more frequent after intra-abdominal operations. ...

In SLE, Renal Damage Is No. 1 Death Predictor

SAN FRANCISCO—Preventing renal damage in patients with systemic lupus erythematosus (SLE) may be critical to lowering their mortality rate, according to a new report.

Overnight HD Could Improve Outcomes

PHILADELPHIA—Hemodialysis (HD) patients who undergo dialysis for eight hours overnight three times a week may reduce their death risk by nearly 80% compared with conventional ...

Post-MI Death Risk Differs by Race

PHILADELPHIA—African-Americans CKD patients have significantly worse survival following an acute MI than their Caucasian counterparts, researchers have found.

Protein Diets May Offer Similar Survival

Tighter restriction of protein intake does not increase the likelihood of survival among CKD patients not yet on dialysis, according to an Italian study that ...

Two Drugs Better than One for LUTS

Combination therapy with tamsulosin and extended-release oxybutynin is superior to tamsulosin alone in treating men with lower urinary tract symptoms (LUTS), data show.

Dietary Fat May Hike RCC Risk

Increased levels of dietary fat intake are associated with a significantly increased risk of renal cell carcinoma (RCC), according to researchers.

Behavioral Therapy Works for Depression

PHILADELPHIA—Cognitive behavioral therapy may help combat depression and improve quality of life (QOL) for dialysis patients, a study shows.

New Approach May Predict IUI Success

SAN FRANCISCO—Multiplying total motile sperm count by the percent of normal sperm determined by strict morphology (TM×SM) may be a significant predictor of pregnancy when ...

ART Informed Consent Form Developed

The Society for Assisted Reproductive Technology (SART) has developed an informed consent form for use by physicians when offering a host of assisted reproductive technology ...

Robot Helps Fix Vesicovaginal Fistulas

Robot-assisted repair of recurrent supratrigonal vesicovaginal fistulas achieves excellent results with few complications, according to researchers.

Urine Assay for Prostate Cancer Advances

SAN DIEGO—A commercial assay may prove to be valuable for determining which men with elevated prostate-specific antigen (PSA) levels or an abnormal digital rectal exam ...

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