Nocturnal Polyuria Highly Prevalent in Men with LUTS

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Nearly 55% of men with lower urinary tract symptoms suffer from nocturnal polyuria, according to a study conducted in Italy.
Nearly 55% of men with lower urinary tract symptoms suffer from nocturnal polyuria, according to a study conducted in Italy.

PHILADELPHIA—More than half of men with lower urinary tract symptoms (LUTS) have nocturnal polyuria (NP), but it is severe in about 10% of cases, investigators reported at the International Continence Society's 2018 annual meeting.

The findings are from a prospective study of 162 men with LUTS who completed both the International Prostate Symptom Score (IPSS) questionnaire and frequency volume chart (FVC) for 3 days. Silvia Bassi, MD, Azienda Ospedaliera Universitaria Integrata of Verona, Italy, and colleagues, found that 54.9% of patients had NP, defined as nocturnal polyuria index (NPi) greater than 33%, Severe NP, defined as an NPi greater than 50%, was present in 9.9%.

The investigators based their NP assessments using 3 days of information on a frequency volume chart (FVC).

NP prevalence varied by age group. It was 64.7%, 48.5%, and 56.4% among men aged less than 65 years, 65 to 74 years, and 75 years or older, respectively. Severe NP was present in 2.9%, 6.0%, and 17.7%, respectively.

The authors found no significant difference among men with and without NP with regard to peak flow and post-void residual volume of urine.

NP was significantly associated with higher median IPSS domain 7 (nocturia) and total IPSS scores, but did not influence IPSS domain 2 (frequency) and domain 8 (bother) scores, according to the investigators.

Reference

Bassi S, Rubilotta E, Balzarro M, et al. Nocturnal polyuria in males with LUTS: prevalence and role of the IPSS and uroflowmetry in the outpatients evaluation. An observational, prospective, double-centre study. Data presented at the International Continence Society's 2018 annual meeting in Philadelphia, August 28–31. Abstract 100.

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