Neuropathic Detrusor Underactivity More Common in Women

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Among patients with detrusor underactivity, 14% of women had neuropathic causes compared with only 2% of men.
Among patients with detrusor underactivity, 14% of women had neuropathic causes compared with only 2% of men.

PHILADELPHIA—Detrusor underactivity (DU) due to neuropathic causes is more common in women than men, according to study findings presented at the International Continence Society's 2018 annual meeting.

Among 1155 patients undergoing urodynamic assessment, investigators identified 440 (38%) who had DU (264 women and 176 men). Neuropathic DU was present in 61 women (14%) compared with only 9 men (2%), a significant difference between the sexes, Huriye Kocadag and colleagues at University College London Hospitals NHS Foundation, London, reported. In addition, women with non-neuropathic DU were significantly younger than their male counterparts (median 53 vs 65 years).

The investigators also identified risk factors non-neuropathic DU. These include previous stress urinary incontinence (SUI), pelvic organ prolapse (POP), or pelvic surgery in women and prior radical prostatectomy (RP) in men.

Of the 203 women with had non-neuropathic DU, 45 (22%) had previous stress SUI/POP surgery and 36 (18%) had previous pelvic surgery. Of the 167 men with non-neuropathic DU, 60 (36%) had a prior RP.

Reference

Kocadag H, Trimboli M, Axell RG, et al. The aetiology of detrusor underactivity. Data presented at the International Continence Society's 2018 annual meeting in Philadelphia, August 28 – 31. Abstract 179.

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