Hypogonadism

Testosterone Therapy May Ease Depressive Symptoms

Testosterone Therapy May Ease Depressive Symptoms

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Meta-analysis suggests that testosterone treatment enhances mood in hypogonadal and eugonadal men.

Study: TRT May Improve Mobility, But Not Fall Risk

Study: TRT May Improve Mobility, But Not Fall Risk

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In a study, older men with difficulty walking or climbing stairs reported better physical function after testosterone therapy.

Auto-Injected Testosterone May Address Some TRT Shortcomings

Auto-Injected Testosterone May Address Some TRT Shortcomings

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Single-dose disposable auto injector approved for once-weekly subcutaneous administration of testosterone may cut down on potential problems associated with other options.

Testosterone Therapy Not Linked to Higher Cardiovascular Risks

Testosterone Therapy Not Linked to Higher Cardiovascular Risks

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In a recent meta-analysis, testosterone therapy was not associated with major or minor adverse cardiovascular events.

TRT May Reduce Mortality Without Improving CV Health in Diabetes

TRT May Reduce Mortality Without Improving CV Health in Diabetes

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In a study, reduced mortality was found among TRT users with type 2 diabetes after adjustment for cardiovascular risk factors.

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

New Testosterone Replacement Therapy Approved for At-Home Self-Administration

Xyosted carries a Boxed Warning regarding blood pressure increases that may potentially increase the risk for major adverse cardiovascular events.

Prostate Cancer Risk Reduced in Men with Very Low Free Testosterone

Prostate Cancer Risk Reduced in Men with Very Low Free Testosterone

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Men in the bottom 10th of free testosterone level vs those with higher levels were found to have a 23% decreased risk of prostate cancer.

Testosterone Prescribing Declining in the US

Testosterone Prescribing Declining in the US

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From 2013 to 2016, the relative decrease in testosterone prescriptions was 48% among established testosterone users and 62% among new users.

Low Testosterone Linked to Sugar-Sweetened Beverages

Low Testosterone Linked to Sugar-Sweetened Beverages

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Among men aged 20-39 years, those in the top quartile of sugar-sweetened beverage intake had 2.3-fold greater odds of low testosterone than those in the bottom quartile.

Testosterone Levels May Be Determined in Childhood

Testosterone Levels May Be Determined in Childhood

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Children who migrated to the UK from Bangladesh before puberty and Bangladeshis born in the UK had significantly higher levels of testosterone compared with life-long residents of Bangladesh.

AUA Issues New Guidelines on Testosterone Deficiency

AUA Issues New Guidelines on Testosterone Deficiency

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The new guidelines focus on accurate assessment and proper monitoring.

Dining Out Linked to Phthalates Exposure in US Population

Dining Out Linked to Phthalates Exposure in US Population

Teen high consumers of food outside the home had 55% higher androgen-disruptor levels.

Testosterone Therapy Guidelines Updated

Testosterone Therapy Guidelines Updated

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Screening and treating all healthy men older than 65 years with testosterone is discouraged.

Low Sperm Count Linked With Cardiometabolic Conditions, Hypogonadism

Low Sperm Count Linked With Cardiometabolic Conditions, Hypogonadism

Low sperm counts linked to hypogonadism, higher BMI, hypertension, dyslipidemia, metabolic syndrome

Testosterone Replacement Therapy Does Not Raise CV Risks

Testosterone Replacement Therapy Does Not Raise CV Risks

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A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.

Testosterone Therapy May Reduce PCa Risk in Hypogonadal Men

Testosterone Therapy May Reduce PCa Risk in Hypogonadal Men

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In a study of hypogonadal men, those who received testosterone therapy had a lower incidence of prostate cancer than those who did not.

Testosterone Therapy May Lower Prostate Cancer Incidence

Testosterone Therapy May Lower Prostate Cancer Incidence

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Hypogonadal men who received testosterone replacement therapy had a lower incidence of prostate cancer than those who did not, and their cancers were less severe.

Testosterone Patterns Predict Prostate Cancer Risk

Testosterone Patterns Predict Prostate Cancer Risk

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The later a man's testosterone level dropped below 12.1 nmol/L, the lower his lifetime risk for prostate cancer.

Testosterone Rx May be Influenced by Provider, Site

Testosterone Rx May be Influenced by Provider, Site

Testosterone use was also more likely at sites located in the West vs the Northeast and for care received at a community-based outpatient clinic versus a medical center.

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

Hypogonadism Ups MetS Risk in Testicular Cancer Patients

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Hypogonadal testicular cancer survivors had 15 times higher odds of metabolic syndrome than their eugonadal counterparts.

Low Testosterone Tied to Anemia Risk in Men With Type 2 Diabetes

Low Testosterone Tied to Anemia Risk in Men With Type 2 Diabetes

In type 2 diabetic male patients, a low testosterone level was found to be associated with anemia. These findings are consistent with previous reports.

TRT Does Not Appear to Increase PCa Risk

TRT Does Not Appear to Increase PCa Risk

A population-based study showed no association between total prostate cancer risk and testosterone replacement therapy (TRT).

Testosterone Therapy Does Not Improve Cognitive Function

Testosterone Therapy Does Not Improve Cognitive Function

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Study of older hypogonadal men does not support use of TRT to improve memory, according to researchers.

Anemia, Bone Density Improve With Testosterone Replacement

Anemia, Bone Density Improve With Testosterone Replacement

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Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.

Testosterone Replacement May Lower Cardiovascular Risks

Testosterone Replacement May Lower Cardiovascular Risks

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In a large study, testosterone replacement therapy was associated with a 33% lower risk of cardiac and stroke events among hypogonadal men.

Normal Testosterone Range Defined

Normal Testosterone Range Defined

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The normal range for total testosterone is 264 to 916 ng/dL for healthy men ages 19 to 39 with a body mass index below 30 kg/m2.

Venous Thromboembolism Risk Up in TRT Initiators

Venous Thromboembolism Risk Up in TRT Initiators

Risk peaks in the first 6 months of hormone treatment, but overall odds are low.

2 Percent Daily Testosterone Shows 6-Month Efficacy

2 Percent Daily Testosterone Shows 6-Month Efficacy

Once-daily T-sol administered for 6 months did not indicate new safety concerns, and the outcomes of low sex drive and low energy showed further improvement.

Hypogonadism Ups Progression Risk in Men With Low-Risk PCa

Hypogonadism Ups Progression Risk in Men With Low-Risk PCa

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New findings have potential implications regarding patient selection for active surveillance.

FDA Adds Abuse Warning to All Testosterone Products

FDA Adds Abuse Warning to All Testosterone Products

The new FDA warning alerts prescribers to the abuse potential of testosterone.

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