Despite research suggesting that there may be increased cardiovascular risk from off-label prescription testosterone use, usage in men with coronary artery disease remains higher than in men without coronary artery disease.
Considerable increase seen from 1997 through 2016, especially in direct-to-consumer advertising
Hypogonadism and serum testosterone evaluation nearly doubled the odds a man would undergo varicocelectomy.
In a study, the rate of deep vein thrombosis in treated hypogonadal men was just 0.8% over 2 years of follow-up.
Prior to starting Xyosted, the patient's baseline cardiovascular risk should be considered and blood pressure should be adequately controlled.
Meta-analysis suggests that testosterone treatment enhances mood in hypogonadal and eugonadal men.
In a study, older men with difficulty walking or climbing stairs reported better physical function after testosterone therapy.
Single-dose disposable auto injector approved for once-weekly subcutaneous administration of testosterone may cut down on potential problems associated with other options.
In a recent meta-analysis, testosterone therapy was not associated with major or minor adverse cardiovascular events.
In a study, reduced mortality was found among TRT users with type 2 diabetes after adjustment for cardiovascular risk factors.
Xyosted carries a Boxed Warning regarding blood pressure increases that may potentially increase the risk for major adverse cardiovascular events.
Men in the bottom 10th of free testosterone level vs those with higher levels were found to have a 23% decreased risk of prostate cancer.
From 2013 to 2016, the relative decrease in testosterone prescriptions was 48% among established testosterone users and 62% among new users.
Among men aged 20-39 years, those in the top quartile of sugar-sweetened beverage intake had 2.3-fold greater odds of low testosterone than those in the bottom quartile.
Children who migrated to the UK from Bangladesh before puberty and Bangladeshis born in the UK had significantly higher levels of testosterone compared with life-long residents of Bangladesh.
The new guidelines focus on accurate assessment and proper monitoring.
Teen high consumers of food outside the home had 55% higher androgen-disruptor levels.
Screening and treating all healthy men older than 65 years with testosterone is discouraged.
Low sperm counts linked to hypogonadism, higher BMI, hypertension, dyslipidemia, metabolic syndrome
A large study of middle-aged men found that testosterone replacement therapy is associated with a small but significant decrease in cardiovascular risk and an increased risk of obstructive sleep apnea.
In a study of hypogonadal men, those who received testosterone therapy had a lower incidence of prostate cancer than those who did not.
Hypogonadal men who received testosterone replacement therapy had a lower incidence of prostate cancer than those who did not, and their cancers were less severe.
The later a man's testosterone level dropped below 12.1 nmol/L, the lower his lifetime risk for prostate cancer.
Testosterone use was also more likely at sites located in the West vs the Northeast and for care received at a community-based outpatient clinic versus a medical center.
Hypogonadal testicular cancer survivors had 15 times higher odds of metabolic syndrome than their eugonadal counterparts.
In type 2 diabetic male patients, a low testosterone level was found to be associated with anemia. These findings are consistent with previous reports.
A population-based study showed no association between total prostate cancer risk and testosterone replacement therapy (TRT).
Study of older hypogonadal men does not support use of TRT to improve memory, according to researchers.
Older men on TRT versus placebo for 1 year had improved hemoglobin levels and volumetric bone mineral density and estimated bone strength.
In a large study, testosterone replacement therapy was associated with a 33% lower risk of cardiac and stroke events among hypogonadal men.
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