Latest Hyperphosphatemia News
A new study found that 24-hour urine phosphorus is inversely related to whole-body retention, but is not related to net intestinal absorption.
In a controlled study, a high-phosphate diet increased systolic and diastolic blood pressure and pulse rate in people with normal renal function.
Highest vs lowest quartile of serum phosphorus is independently associated with a nearly 3-fold increased risk of diabetic nephropathy progression.
Patients on hemodialysis who achieved serum phosphate levels below 4.5 mg/dL experienced a decrease in intact fibroblast growth factor 23.
In a study, hemodialysis patients who used phosphate binders had up to a 44% decreased risk of dying from infection than those who did not use the drugs.
Clinicians were able to reduce doses of erythropoiesis-stimulating agents and intravenous iron.
Patients with serum phosphate levels of 4.9 mg/dL or higher upon admission had the worst survival.
Midweek serum phosphate levels can differ from levels measured after a weekend.
Median intact FGF-23 significantly fell by 64% over 1 year of treatment with sucroferic oxyhydroxide or sevelamer.
Meta-analysis shows that nicotinic acid could be a good alternative or add on to traditional phosphate binders, but it is associated with a high rate of adverse events.
In a meta-analysis, hemodialysis patients using lanthanum carbonate to lower phosphorus levels had a 55% decreased risk of death compared with those taking other binders.
A serum phosphate control target of 4.5 mg/dL or below in hemodialysis patients was accompanied by a decline in fibroblast growth factor 23.
Mean 25-hydroxyvitamin D levels did not differ significantly among groups receiving phosphate binders or dietary therapy.
In a study, intact parathyroid hormone levels fell by nearly 10% over 6 months in hemodialysis patients who received intensive treatment for hyperphosphatemia.
Excess calcium following a meal may be deposited in soft tissue and blood vessels, researchers hypothesize.
NEPHROLOGY & UROLOGY NEWS
- Acute Kidney Injury (AKI)
- Chronic Kidney Disease (CKD)
- Contrast Nephropathy
- Cardiovascular Disease (CVD)
- Diabetic Nephropathy
- End-stage Renal Disease (ESRD)
- Lupus Nephritis
- Peritoneal Dialysis
- Secondary Hyperparathyroidism (SHPT)