Australian researchers have proposed that transperineal (TP) prostate biopsies be offered an option to all men for whom a prostate biopsy is indicated.

The reason, they say, is that TP—although it is more involved and more costly than transrectal ultrasonography (TRUS)-guided biopsy—it is associated with a negligible risk of sepsis, whereas the rate of sepsis resulting from TRUS-guided biopsy is rising, with an increasing proportion of cases involving multidrug-resistant bacteria.

The researchers, led by Jeremy P. Grummet, MBBS, MS, of Monash University, Melbourne, analyzed the outcomes of 245 TP biopsies and found a zero rate of hospital re-admission for sepsis, according to an online report in BJU International.

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