| HYPERTENSION TREATMENTS: ORAL CCBs | |||||
|---|---|---|---|---|---|
| Generic | Brand | Strength | Form | Initial Adult Dose | |
| BENZOTHIAZEPINES | |||||
| diltiazem | Cardizem LA | 120mg, 180mg, 240mg, 300mg, 360mg, 420mg | ext‑rel tabs | 180−240mg once daily; adjust at 2wk intervals; max 540mg/day | |
| Cardizem CD |
120mg, 180mg, 240mg, 300mg, 360mg | ext‑rel caps | 180−240mg once daily; adjust at 2wk intervals; max 480mg/day | ||
| Tiazac | 120mg, 180mg, 240mg, 300mg, 360mg, 420mg | ext‑rel caps | 120−240mg once daily; adjust at 2wk intervals; max 540mg/day | ||
| DIHYDROPYRIDINES | |||||
| amlodi– pine |
Norvasc | 2.5mg, 5mg, 10mg | tabs | 5mg daily; adjust at 7−14 day intervals; max 10mg daily | |
| felodipine | — | 2.5mg, 5mg, 10mg | ext‑rel tabs | 5mg once daily; adjust at 2wk intervals; max 10mg daily | |
| isradipine | — | 5mg, 10mg | ext‑rel tabs | 5mg daily, alone or with a thiazide diuretic; titrate by 5mg/day at 2–4wk intervals; max 20mg/day | |
| nicardi– pine |
— | 20mg, 30mg | caps | ≥18yrs: 20mg 3 times daily; adjust at intervals of at least 3 days; max 120mg daily | |
| nifedipine | Adalat CC | 30mg, 60mg, 90mg | ext‑rel tabs | 30mg once daily; titrate over 7−14 days; max 90mg/day | |
| Afeditab CR | 30mg, 60mg | ext‑rel tabs | 30mg once daily, titrate over 7−14 days; max 90mg/day | ||
| Procardia XL |
30mg, 60mg, 90mg | ext‑rel tabs | 30 or 60mg once daily, titrate over 7−14 days; max 120mg/day | ||
| nisoldi– pine |
Sular | 8.5mg, 17mg, 34mg | ext‑rel tabs | 17mg once daily; may increase by 8.5mg weekly; max 34mg/day | |
| DIPHENYLALKYLAMINES | |||||
| verapamil | Calan | 40mg, 80mg+, 120mg+ | tabs | ≥18yrs: 80mg 3 times daily; usual max 360mg/day in divided doses. Elderly or small patients: 40mg 3 times daily | |
| Calan SR | 120mg, 180mg+, 240mg+ | sust-rel caplets | ≥18yrs: 180mg in the AM; may titrate to max 480mg/day in divided doses. Elderly or small patients: 120mg in the AM | ||
| Verelan | 120mg, 180mg, 240mg, 360mg | sust-rel caps | ≥18yrs: Usually 240mg daily in the AM; adjust in 120mg increments; max 480mg/day | ||
| Verelan PM | 100mg, 200mg, 300mg | controlled onset ext‑rel tabs | 200mg once daily at bedtime; may titrate upwards in steps to 300mg, then 400mg if needed | ||
| NOTES | |||||
|
Key: + = scored Not an inclusive list of medications, official indications and/or doses. Please see drug monograph at www.eMPR.com and/or contact company for full drug labeling. Individualize dose. Initially may start at lower doses in certain patient populations. May be confused with other products with similar names. Ensure that the patient receives the appropriate product. With few exceptions, ext-rel and sust-rel products should not be crushed, chewed, or divided to preserve the products’ release characteristics. (Rev. 1/2018) |
|||||
This article originally appeared on MPR
