Study authors discuss the uncertainties and challenges in the interpretation of the CREDIBLE-CR trial and benefit-risk considerations for the use of cefiderocol in clinical practice.
Study findings suggest that oral β-lactam antibiotics as step-down treatment following treatment with parenteral antibiotics may treat bacteremia from a urinary source when fluoroquinolones or trimethoprim-sulfamethoxazole use is limited by adverse effects or resistance.
Research authors assessed the safety and efficacy of intravesical bacteriophage therapy compared to placebo and current standard of care for the treatment of urinary tract infection in patients undergoing transurethral resection of the prostate.
The observational study aimed to determine the association between fluoroquinolone use and the risk of aortic aneurysm or aortic dissection while taking into account potential confounding.