Researchers conducted a study to assess the effect of an antibiotic stewardship program on the use of appropriate antibiotic therapy among patients with urinary tract infections in the ED.
MV140 is a sublingual vaccine of whole-cell inactivated bacteria that may be an alternative to frequent antibiotics for recurrent urinary tract infections.
In a study, IV fosfomycin appeared less effective than IV ceftriaxone or meropenem for bacteremic UTI caused by multidrug-resistant E. coli, but the drug may be considered for selected patients with these infections, according to investigators.
Researchers conducted a study to assess the safety and efficacy of aminoglycosides or polymyxin monotherapy for the treatment of adults with complicated urinary tract infections caused by extensively drug-resistant Pseudomonas aeruginosa.
The application includes data from the phase 3 ADAPT-PO trial, which evaluated the efficacy and safety of tebipenem HBr in 868 adults with cUTI or acute pyelonephritis.