Urinary Tract Infections (UTI)

Guidelines Developed for Polymyxin Antibiotic Use

Publish Date March 15, 2019

Polymyxin B recommended for routine use in invasive infections; colistin preferred for lower UTI

Machine Learning Methods Can Detect UTI in Dementia Patients

Publish Date January 29, 2019

Research team used novel algorithms to ID early symptoms of health declines in dementia patients.

SGLT2 Inhibitors and Urinary Tract Infections: What’s the Link?

Publish Date December 19, 2018

For this study, the authors identified randomized controlled trials (RCTs) that compared SGLT2 inhibitors with placebo, no treatment, or another antidiabetic agent and reported on UTI outcome.

Abx-Resistant Enterobacteriaceae Tied to Clinical Failure in UTI

Publish Date November 8, 2018

Poor clinical outcomes linked to extended spectrum cephalosporin-resistant Enterobacteriaceae.

Fluoroquinolones Tied to Increased Risk for Arrhythmia, CV Mortality

Publish Date November 2, 2018

To investigate the risk of cardiovascular adverse effects associated with this antibiotic class, researchers conducted a systematic review, meta-analysis, and network meta-analysis using studies identified through a search of MEDLINE, EMBASE, and the Cochrane Library.

In Complicated UTI, Cefiderocol Noninferior to Imipenem-Cilastin

Publish Date October 31, 2018

Results from phase 2 study in patients with multidrug-resistant Gram-negative uropathogens.

UTI Risk After Urogynecologic Surgery Linked to Bladder Microbiome

Publish Date October 3, 2018

Depletion of Lactobacillus iners in the bladder appears to increase the risk of urinary tract infection following urogynecologic surgery, study finds.

Recurrent Cystitis Possibly Preventable by Drinking More Water

Publish Date October 1, 2018

During a 12-month study, women who drank 1.5 L of water daily in addition to their usual fluid intake reduced their mean number of cystitis episodes nearly by half.

Zemdri Now Treats Complicated UTI, Pyelonephritis

Publish Date August 8, 2018

Zemdri carries a Boxed Warning describing reports of nephrotoxicity, ototoxicity, and neuromuscular blockade, as well as fetal harm if administered during pregnancy.

FDA Approves Drug for Complicated UTIs

Publish Date June 27, 2018

Plazomicin, an aminoglycoside, was approved for treating complicated urinary tract infections in adults due to certain Enterobacteriaceae.