Urinary Tract Infections (UTI)

Some Patients Have Increase in Cardiac Events With Azithromycin

Publish Date October 14, 2020

Risk for cardiac events higher with azithromycin versus amoxicillin in those using QT-prolonging drugs.

Hospital Admissions Not Related to COVID-19 Fell in Early 2020

Publish Date October 9, 2020

From February to April 2020, drop >20% observed for all primary admission diagnoses.

Risk of Cardiac Events With Azithromycin, Amoxicillin Compared

Publish Date September 17, 2020

The aim of the study was to use real-world data to compare the risk of cardiac events in new users of azithromycin vs amoxicillin.

Risk of Aortic Aneurysm, Dissection With Fluoroquinolones Examined

Publish Date September 15, 2020

The observational study aimed to determine the association between fluoroquinolone use and the risk of aortic aneurysm or aortic dissection while taking into account potential confounding.

Protocolized Urine Sampling Reduces Catheter-Associated UTI

Publish Date September 11, 2020

Investigators sought to determine whether a new protocol for urine sampling and testing lowers rates of catheter-associated urinary tract infections.

Menopausal Hormonal Therapy May Cut UTI Risk

Publish Date July 23, 2020

New study is the first focused analysis of bacterial diversity in the urogenital tract of postmenopausal women, according to investigators.

Shorter Antibiotic Treatment Duration Effective for Acute Uncomplicated Cystitis

Publish Date July 1, 2020

A team of investigators conducted a systematic review and meta-analysis to assess whether a shorter-than-recommended duration of antibiotic treatment can be effective for the management of acute uncomplicated cystitis.

Trial Comparing Sulopenem to Ertapenem for cUTI Misses End Point

Publish Date June 5, 2020

Findings showed that the trial failed to demonstrate noninferiority, with a responder rate of 67.8% for sulopenem at the test of cure visit compared with 73.9% for ertapenem (difference of -6.1%; [95% CI, -12.0, -0.1])

Novel Antibiotic Combo Beats Piperacillin-Tazobactam in Complicated UTI Trial

Publish Date March 3, 2020

The combination of cefepime, a cephalosporin antibiotic, and enmetazobactam, a novel extended-spectrum β-lactamase inhibitor (Exblifep; Allecra Therapeutics) was found to be superior to piperacillin-tazobactam in the treatment of complicated urinary tract infections (cUTI), including acute pyelonephritis, according to top-line results from the phase 3 ALLIUM trial. The double-blind, non-inferiority study included 1034 patients randomized to…

Cleansing Agent for Reducing Recurrent UTI Risk Now Available OTC

Publish Date March 3, 2020

Theraworx® Protect U-Pak (Avadim Health), a hygiene solution developed to address risk factors associated with recurrent urinary tract infections (UTIs), is now available in retail pharmacies.