(HealthDay News) — Single-incision mini-slings are noninferior to mid-urethral slings for women with stress urinary incontinence, according to a study published in the New England Journal of Medicine.
Mohamed Abdel-Fattah, MD, from the University of Aberdeen in the United Kingdom, and colleagues compared mini-slings to mid-urethral slings among women at 21 UK hospitals during 36 months of follow-up in a pragmatic, noninferiority, randomized trial. A total of 298 women were randomly assigned to receive mini-slings and 298 were randomly assigned to mid-urethral slings.
The researchers found that success was reported by 79.1 and 75.6% of patients in the mini-sling and mid-urethral sling groups, respectively, at 15 months (adjusted risk difference, 4.6 percentage points; 9% confidence interval [CI], −2.7 to 11.8; P <.001 for noninferiority). Success was reported by 72 and 66.8% of patients, respectively, at the 36-month follow-up (adjusted risk difference, 5.7 percentage points; 95% CI, −1.3 to 12.8). The percentage of patients with groin or thigh pain at 36 months was 14.1 and 14.9% for those with mini-slings and mid-urethral slings, respectively; the percentage with tape or mesh exposure was 3.3 and 1.9%, respectively, during the 36-month follow-up. The groups had similar outcomes with respect to quality of life and sexual function, apart from dyspareunia, which was reported by 11.7 and 4.8% in the mini-sling and mid-urethral sling groups, respectively.
Continue Reading
“Adjustable anchored mini-slings were noninferior to tension-free mid-urethral slings with respect to patient-reported success at 15 months, and the between-group difference remained similar at 36 months,” the authors write.
Abstract/Full Text (subscription or payment may be required)
