Upper tract urothelial carcinoma

The biggest reluctance to using these stents is their cost, which is approximately six times that of their polymer counterparts. At least two studies, however, have found economic benefit when the number of stent changes the patient undergoes is considered.

Prophylactic Ureteral Stenting Linked to Upper Tract Urothelial Carcinoma

April 14, 2021

In current urological practice, clinicians decide whether to place a ureteral stent or nephrostomy, but evidence-based treatment guidance is needed.

Radiation Therapy Increases Survival in Metastatic Urothelial Carcinoma

February 11, 2021

Patients with metastatic urothelial carcinoma have significantly longer overall survival when treated with a combination of radiotherapy and chemotherapy compared with chemotherapy alone, a study found.

Bone Metastases Predict Worse mUC Immunotherapy Outcomes

February 11, 2021

The presence of bone metastases is associated with shorter survival among patients who received single-agent immunotherapy for metastatic urothelial carcinoma.

Cytoreductive Surgery May Have a Role in Treating Metastatic UTUC

January 29, 2021

A study of patients with metastatic upper tract urothelial carcinoma demonstrated that those who underwent cytoreductive surgery after chemotherapy had significantly improved survival compared with those who received chemotherapy alone.

Liver Metastases in Advanced GU Cancer Predict Poor Response to ICI Therapy

January 26, 2021

Patients who receive treatment with immune checkpoint inhibitors for advanced renal cell carcinoma and urothelial carcinoma are more likely to experience disease progression and death if they have liver metastases, a study found.

A patient undergoes cancer-related surgery.

Segmental Ureterectomy May Be an Option for High-Risk Ureteral Tumors

October 12, 2020

In patients with high-risk tumors, those treated with segmental ureterectomy did not have worse overall survival compared with those who underwent radical nephroureterectomy.

Multiple patients having chemotherapy in a room

Neoadjuvant and Adjuvant Chemo More Effective Than RNU Alone in UTUC

October 2, 2020

As current guidelines only include a weak recommendation to offer perioperative chemotherapy to patients with muscle-invasive upper tract urothelial carcinoma, a new meta-analysis including evidence up to February 2020 provides potentially useful information.