Upper Tract Urothelial Carcinoma

IMRT a Possible Option for Upper Tract Urothelial Carcinoma

Publish Date January 15, 2020

In a small pilot study, all 16 UTUC patients experienced a complete or partial response to IMRT.

Lymph Node Dissection Ups Survival in Higher-Stage UTUC

Publish Date January 14, 2020

A study found that patients with more advanced-stage upper tract urothelial carcinoma had a higher prevalence of lymph node metastasis.

PTRF Biomarker May Predict UTUC Progression, Survival

Publish Date January 8, 2020

In a study, high PTRF expression indicated clinically aggressive UTUC in both Taiwanese and Caucasian patients.

Upper Tract Urothelial Cancer Treatment Granted Priority Review

Publish Date December 19, 2019

In a phase 3 trial, mitomycin gel for instillation showed a complete response rate of 59% of patients with low-grade upper tract urothelial cancer.

Segmental Ureterectomy an Option in Some UTUC Cases

Publish Date November 18, 2019

A meta-analysis comparing segmental ureterectomy and radical nephroureterectomy for UTUC suggests that selected patients, such as those with low-risk ureteral tumors, might benefit from segmental ureterectomy.

Neoadjuvant Chemo Leads to Downstaging in Some UTUC Cases

Publish Date November 14, 2019

Chemotherapy should be considered part of multi-modal treatment for nonmetastatic UTUC patients when clinically feasible, according to researchers.

Adjuvant Chemotherapy Improves Outcomes in Locally Advanced UTUC

Publish Date November 6, 2019

For some UTUC patients, adjuvant chemotherapy may improve survival over radical nephroureterectomy alone,

Preoperative Pyuria Predicts Bladder Recurrence After UTUC Surgery

Publish Date October 25, 2019

In a small study of patients without a history of bladder cancer who undergo radical nephroureterectomy for upper tract urothelial carcinoma, preoperative pyuria was associated with a 1.7-fold increased risk of intravesical recurrence, a study found.

Variant Histology Worsens UTUC Outcomes, Study Finds

Publish Date September 5, 2019

Variant histology upper tract urothelial carcinoma (UTUC) is associated with a 2 times higher risk of cancer-specific mortality than pure UTUC, according to a new review and meta-analysis.

Combo Shows Promise as Alternative for Metastatic Urothelial Carcinoma

Publish Date August 15, 2019

In a phase 2 trial, a regimen of gemcitabine plus eribulin compared favorably with other regimens for the first-line treatment of cisplatin-ineligible patients with metastatic urothelial carcinoma.