In a small study, single-dose instillation of mitomycin C immediately following therapeutic ureteroscopy for upper tract urothelial carcinoma was associated with an 87% decreased risk of urothelial recurrence.
Preoperative diagnostic ureteroscopy (URS) before radical nephroureterectomy for upper tract urothelial carcinoma (UTUC) is a risk factor for intravesical recurrence, according to investigators. In a study of 453 patients with UTUC undergoing radical nephroureterectomy (RNU), a significantly higher proportion of patients who underwent preoperative URS experienced intravesical recurrence (IVR) than those who did not (43.8%…
In a study, patients with kidney failure due to urinary tract cancers had an increased mortality risk and decreased access to kidney transplantation if they had active malignancy at the start of dialysis.
Adjuvant platinum-based chemotherapy for upper tract urothelial carcinoma within 90-days of nephroureterectomy improves disease-free and metastasis-free survival compared with surveillance, a study found.
Tumor diameter and stage are independent risk factors for intravesical recurrence of organ-confined upper tract urothelial carcinoma (UTUC) following radical nephroureterectomy (RNU), according to a new study. In a retrospective study of patients with organ-confined UTUC who underwent RNU combined with bladder cuff resection, investigators propensity score matched 42 patients who experienced intravesical recurrence (IVR)…
In a study, patients with upper tract urothelial carcinoma and pathologic vascular invasion who received adjuvant chemotherapy had significantly longer overall survival than those who did not receive adjuvant chemotherapy.
High CONUT scores were associated with adverse clinicopathological characteristics and worse survival in patients with localized upper tract urothelial carcinoma.
In a study of patients with upper tract urothelial carcinoma, variant vs conventional histology predicted worse survival.
Sterile pyuria may be a marker of inflammation, which is known to influence carcinogenesis.
Intravesical incision of the bladder cuff may be superior to other distal ureteral management techniques, according to investigators.