High CONUT scores were associated with adverse clinicopathological characteristics and worse survival in patients with localized upper tract urothelial carcinoma.
In a study of patients with upper tract urothelial carcinoma, variant vs conventional histology predicted worse survival.
Sterile pyuria may be a marker of inflammation, which is known to influence carcinogenesis.
Intravesical incision of the bladder cuff may be superior to other distal ureteral management techniques, according to investigators.
Some patients with high-risk upper tract urothelial carcinoma experience pathologic downstaging following preoperative chemotherapy.
In a small pilot study, all 16 UTUC patients experienced a complete or partial response to IMRT.
A study found that patients with more advanced-stage upper tract urothelial carcinoma had a higher prevalence of lymph node metastasis.
In a study, high PTRF expression indicated clinically aggressive UTUC in both Taiwanese and Caucasian patients.
In a phase 3 trial, mitomycin gel for instillation showed a complete response rate of 59% of patients with low-grade upper tract urothelial cancer.
A meta-analysis comparing segmental ureterectomy and radical nephroureterectomy for UTUC suggests that selected patients, such as those with low-risk ureteral tumors, might benefit from segmental ureterectomy.