Obese patients who undergo radical prostatectomy (RP) for localized prostate cancer fare no worse than normal-sized patients with respect to perioperative complications and oncologic outcomes, new findings suggest.

John Trachtenberg, MD, of Princess Margaret Hospital in Toronto, and colleagues reviewed data from 491 men who underwent RP from 2004-2007, dividing subjects into three groups according to BMI (kg/m2): less than 25, 25-30 (overweight), and greater than 30 (obese). Early complication rates, positive surgical margin rates, and pathologic Gleason scores were similar among the three groups, as were the rates of adjunctive treatments and biochemical recurrence, the researchers reported in the International Journal of Urology (2010;17:727-732). Obese subjects, however, had longer operating times (146 vs. 135 minutes for non-obese patients) and greater estimated blood loss (640 vs. 504 mL). Transfusion rates did not differ.

“In light of the present findings, it might be necessary to revisit some of our misconceptions about surgical outcomes in obese patients and show that this population should not be excluded from surgery on the basis of BMI alone,” the authors concluded.

Continue Reading