Men who have physically demanding jobs may be at lower risk of prostate cancer (PCa) than those who do not, according to a recent report.
A case-control study examining data from the Nordic Occupational Cancer Study found that men with low, medium, and high cumulative exposure to perceived physical workload (PPWL) had 10%, 12%, and 7% lower risk of PCa, respectively, than those with no PPWL exposure, Jorma Sormunen, MD, of the University of Tampere and Tampere University Hospital in Tampere, Finland, and colleagues reported in the Asian Pacific Journal of Cancer Prevention. Adjustment for socioeconomic status did not substantially change results. Dr Sormunen and his team said they found no evidence of a dose-response relationship between PPWL and PCa.
The authors concluded that their study corroborates earlier research showing that lack of physical activity and a sedentary lifestyle seem to be associated with an elevated risk of PCa compared with any level of physical activity.
The study population consisted of 239,835 PCa cases and 1,199,175 controls from Finland and Sweden. The average age at PCa diagnosis was 72.2 years.
Sormunen J, Talbov M, Sparén P, et al. Perceived physical strain at work and incidence of prostate cancer—a case-control study in Sweden and Finland. Asian Pac J Cancer Prev. 2018;19:2331-2335.