Preoperative pelvic floor muscle exercise (PFME) may improve early continence and quality of life (QoL) outcomes after radical prostatectomy (RP) for localized prostate cancer, an Italian study found.
Antonia Centemero, MD, and colleagues at Vita-Salute University in Milan, randomly assigned 59 patients to start PFME 30 days before radical prostatectomy and to continue it postoperatively (group A) and 59 to start PFME postoperatively (group B). The primary outcome measure was self-reported continence at one and three months after surgery.
After one month, 26 patients (44.1%) in group A were continent compared with 12 patients (20.3%) in group B, according to findings published in European Urology (published online ahead of print). At three months, 35 men in group A (59.3%) and 22 in group B (37.3%) were continent.
Patients in group A had significantly better mean QoL scores on the International Continence Society male short form than patients in group B (14.6 vs. 18.3 at one month and 8.1 vs. 12.2 at three months).
Additionally, 15 patients in group A (25.4%) had a 24-hour pad test weight greater than 150 grams compared with 20 patients in group B (33.9%) at one month. At three months, 10 patients in group A ((16.9%) had a 24-hour pad test weight greater than 150 grams compared with 19 patients in group B (32.2%). At both time points, the between-group differences were statistically significant.