Researchers who have uncovered the ‘monstrous’ hidden nature of a molecule involved in prostate cancer say the findings could herald a new form of personalised medicine for patients, with doctors able to use the same molecular target for diagnosis and treatment. In a series of two papers just published*, researchers at The University of Hull have shown that prostate cancer patients who have Endo180 protein present in their tumours tend to have more severe disease.

Around 65 per cent of men with Endo180 positive tumours died within 5 years of diagnosis, compared to just 39 per cent who did not have Endo180. These results suggest that Endo180 contributes to thousands of prostate cancer deaths. And the team have also uncovered why this might be.

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