Glycemic Control May Predict Prostate Cancer Pathology

Hemoglobin A_1c (HbA_1c) levels prior to radical prostatectomy (RP) may predict tumor aggressiveness in prostate cancer patients with diabetes, Korean researchers reported in The Prostate (2009;69:820-826).

They reviewed data on 740 patients who underwent RP for clinically localized prostate cancer.

Among the 89 diabetic patients, those with a preoperative HbA_1c level of 6.5% or higher had significantly increased rates of extraprostatic extension and pathologic Gleason scores of 7 or above compared with those whose HbA_1c level was below 6.5%.

From the March 01, 2009 Issue of Renal and Urology News