For African-Americans, who are at elevated prostate cancer (PCa) risk, baldness at age 30 correlates with prostate cancer, with frontal baldness linked to increased odds of high-stage and high-grade disease, according to a study published online ahead of print in Cancer Epidemiology, Biomarkers & Prevention.

Charnita Zeigler-Johnson, PhD, from the University of Pennsylvania School of Medicine in Philadelphia, and colleagues recruited 318 African-American prostate cancer cases and 219 African-American controls to examine the correlation between early-onset baldness with prostate cancer.

The researchers found that baldness correlated with a 69% increased likelihood of PCa. Frontal baldness correlated with 2.6 times and 2.2 times increased odds of high-stage and high-grade tumors, respectively, with a stronger correlation for men diagnosed before the age of 60 years.

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“African-American men present with unique risk factors including baldness patterns that may contribute to prostate cancer disparities,” the authors write.