Radical prostatectomy (RP) leads to significant changes in the levels of some androgens, Swedish investigators reported in The Prostate (2009; published online ahead of print).

They measured androgen levels in 55 men prior to undergoing RP for localized prostate cancer and in 53 of these patients 90 days after surgery.

The men had significant elevations in serum luteinizing hormone and follicle stimulating hormone and significant decreases in serum and urine dihydrotestosterone.

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