For men with newly diagnosed metastatic castration-resistant prostate cancer, starting with abiraterone plus prednisone followed by enzalutamide upon PSA progression significantly prolongs time to second PSA progression compared with the opposite sequence, a study found.
Strong inverse association found for PTEN-null cancer but not for PTEN-intact cancers
Even though the EMBRACE study adds to the literature, according to authors the “best way” to screen men with germline DNA damage repair abnormalities “remains unclear.”
Plant-based diets might lower risk, animal-based diets containing dairy might raise risk for prostate cancer
Depression and anxiety about cancer recurrence are among the issues that face many men following treatment for prostate cancer.
Patients with low-risk disease more likely to receive nondefinitive therapy at MultiD clinic versus SEER.
Regardless of PSA levels triggering biopsy, no difference in prostate cancer detection at biopsy.
Variety of ethnicities need to be included in studies of germline testing to better understand variants.
Active surveillance (AS) is an appropriate management strategy for black men with favorable-risk prostate cancer (PCa) who adhere to a standardized protocol of regular PSA tests and biopsies, investigators reported. The prospective, multi-institutional cohort Canary Prostate Cancer Active Surveillance Study (PASS), which included 1315 men on AS, found that black men were at no higher…
Traditionally, approaches to the management of patients with nonmetastatic CRPC following radical prostatectomy have been limited.