Early ADT for Recurrent Prostate Cancer Challenged
Men with biochemically recurrent nonmetastatic prostate cancer following radical prostatectomy have long survival times from the time of surgery without hormonal treatment, a study found.
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Data May Support Routine Tumor Testing for HRR Gene Alterations in mCRPC
Almost 28% of men with metastatic castration-resistant prostate cancer harbor alterations in homologous recombination repair genes, a study found. -
Sipuleucel-T Efficacy, Safety in mCRPC Evaluated in Real World Study
The median time from first infusion of sipuleucel-T to death from prostate cancer was 42.7 months. -
Men With High-Risk PCa and Low PSA May Benefit More From Surgery Than Radiation
In a study, radical prostatectomy for men with Gleason 8-10 prostate cancer and low PSA levels was associated with a lower death risk compared with external beam radiation therapy with or without brachytherapy. -
Prospective Study Characterizes PCa Risk Linked to BRCA1, BRCA2 Mutations
For decades, it has been known that the mutations in the tumor suppressor genes BRCA1 and BRCA2 are associated with high risks of breast and ovarian cancer, but a new prospective cohort study provides the strongest evidence to date that these mutations are associated with the development of prostate cancer (PCa). The BRCA2 mutation appears… -
Skeletal-Related Events Common After CRPC Development
Large observational study reveals a 40% cumulative incidence rate of first skeletal-related events following development of castration-resistant prostate cancer.
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Intensity-Modulated Radiation Charges for Prostate Cancer Vary
Mean charge for standard 28-fraction was $111,728.80, 10.1 times the price paid by Medicare.
Low Baseline PSA at Screening a Favorable Sign in Middle-Aged Men
Repeated screening can be less frequent among men aged 55 to 60 years with a low baseline PSA level (below 2.00 ng/mL).
Increasing Vegetable Intake Does Not Slow Prostate Cancer
Behavioral intervention had no impact on time to progression among men with early-stage disease.
AI System Can Detect, Grade Cancer in Prostate Needle Biopsy
AUCs were 0.997, 0.986 for distinguishing between benign, malignant biopsy cores, respectively.
Prostate Cancer Treatment Side Effects Worse With Prostatectomy
In a study, localized prostate cancer patients reported clinically meaningful differences in urinary, bowel, sexual, and hormonal function by management option up to 5 years of follow-up.
Kegel Exercises After Prostate Surgery Called Into Question
Pelvic physical therapy may be more appropriate than Kegel exercises in managing post-radical prostatectomy pain and stress urinary incontinence, according to a new study.
MRI-Guided Transurethral Ultrasound Ablation: Promising Data in Prostate Cancer
MRI-guided TULSA uses a transurethral catheter to precisely apply ultrasound and MRI-guided thermotherapy to ablate cancerous tissue within the prostate gland.
Hospital Admissions for Prostate Biopsy Infections on the Rise
Although infection rates following prostate biopsy have stabilized, the rates of emergency department visits and hospitalizations for post-biopsy infections are increasing, a study found.
Active Surveillance for Low-Risk Prostate Cancer: Can Different Protocols Impact Clinical Outcomes?
Heterogeneity in protocols across centers has contributed to a lack of long-term outcomes for different active surveillance protocols.
New Vaccine Could Delay ADT Use in Stage D0 Prostate Cancer
If the vaccine is shown to work, it may help delay the use of ADT in such patients, Dr Maeng said.
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