PSA Density Plus MRI May Improve Detection of Clinically Significant Prostate Cancer
Combining PSA density with prostate MRI findings improves the predictive performance of PI-RADS in men without a prior prostate cancer diagnosis.
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Prostate Cancer
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4Kscore May Help Predict Adverse Pathology at Radical Prostatectomy
In a study, a higher 4Kscore was significantly associated with a 16% greater risk of biochemical recurrence of prostate cancer following radical prostatectomy. -
SABR Found to Improve Outcomes in Recurrent Oligometastatic HSPC
In patients with recurrent oligometastatic hormone-sensitive prostate cancer, stereotactic ablative radiation therapy decreased the risk of disease progression compared with observation alone, a phase 2 study found. -
Genomic Alterations Linked to Outcomes in mCSPC
DNA sequencing in men with metastatic castration-sensitive prostate cancer revealed alterations in certain signaling pathways that predict worse overall survival and shorter progression time to castration-resistant disease. -
Prostate Cancer Immunotherapy Alone Is Not Enough
So far, prostate cancer immunotherapy has shown only modest benefits. To greatly improve outcomes, immunotherapy will need to be combined with other treatments, according to the authors of a recent review. -
Radiation Therapy After Prostate Surgery Worsens Sexual, Urinary Function
Allowing an approximately 24-month recovery period after prostate surgery before giving radiation therapy may be optimal for preserving erectile function provided oncologic control is not compromised, according to investigators. -
Fewer Systematic Biopsy Cores May Not Lower PCa Detection Rate
In a study of patients undergoing transperineal prostate biopsy, the detection rate of clinically significant prostate cancer did not differ significantly between targeted biopsy (TB) with fewer systematic biopsy (SB) cores and TB with SB of the whole prostate.
Latest Prostate Cancer News
Black Men Have Better Outcomes From Radiation-Based Tx for High-Risk PCa
Black race is associated with improved oncologic outcomes among men undergoing radiation-based therapy for high-risk prostate cancer, new findings suggest.
Fluciclovine PET/CT Improves Prostate Cancer Salvage Radiation Outcomes
Fluciclovine PET/CT plus conventional imaging vs conventional imaging alone to guide radiation therapy for men with recurrent PCa following radical prostatectomy results in improved failure-free survival, according to the first randomized trial comparing the 2 approaches.
Circulating Tumor Cells May Predict Response to Radium-223 in mCRPC
Pretreatment counts of 5 CTCs per 7.5 mL of blood or higher correlated with shorter survival compared with lower counts among men with metastatic castration-resistant prostate cancer treated with radium-223, a study found.
US Incidence of Distant-Stage Prostate Cancer Up, 2010 to 2017
Five-year survival for distant-stage prostate cancer improved from 2011 to 2016.
Understanding the Stigma Experienced by Patients With Prostate Cancer
Interview study reveals men’s perception and concerns related to their prostate cancer journey.
BMD Testing Rates Low in Men Initiating ADT for Prostate Cancer
Odds of BMD testing up with history of osteoporosis, rheumatoid arthritis, bisphosphonate use.
Black Men With Prostate Cancer Found to Be Reluctant to Participate in Trials
Efforts should be made to address patient concerns about clinical trial participation.
Prostate Cancer Metastasizes by Hijacking a Developmental Epigenetic Program
Localized prostate cancer is thought to metastasize by tapping into a developmental program used by its embryonic ancestors.
Radiation for Abdominal, Pelvic Cancers Ups Secondary Sarcoma Risk
Compared with patients who undergo surgery alone for abdominal or pelvic cancers, those who receive radiation and chemotherapy are at elevated risk for secondary sarcomas.
Conservative Prostate Cancer Management May Be Less Durable Among Black Men
Among men on active surveillance or watchful waiting for low- and intermediate-risk prostate cancer (PCa), Blacks had a shorter median time from PCa diagnosis to definitive therapy compared with Whites.
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