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Prostate Cancer

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PSA Density Plus MRI May Improve Detection of Clinically Significant Prostate Cancer

Combining PSA density with prostate MRI findings improves the predictive performance of PI-RADS in men without a prior prostate cancer diagnosis.
4Kscore May Help Predict Adverse Pathology at Radical Prostatectomy

In a study, a higher 4Kscore was significantly associated with a 16% greater risk of biochemical recurrence of prostate cancer following radical prostatectomy.
SABR Found to Improve Outcomes in Recurrent Oligometastatic HSPC

In patients with recurrent oligometastatic hormone-sensitive prostate cancer, stereotactic ablative radiation therapy decreased the risk of disease progression compared with observation alone, a phase 2 study found.
Genomic Alterations Linked to Outcomes in mCSPC

DNA sequencing in men with metastatic castration-sensitive prostate cancer revealed alterations in certain signaling pathways that predict worse overall survival and shorter progression time to castration-resistant disease.
Prostate Cancer Immunotherapy Alone Is Not Enough

So far, prostate cancer immunotherapy has shown only modest benefits. To greatly improve outcomes, immunotherapy will need to be combined with other treatments, according to the authors of a recent review.
Radiation Therapy After Prostate Surgery Worsens Sexual, Urinary Function

Allowing an approximately 24-month recovery period after prostate surgery before giving radiation therapy may be optimal for preserving erectile function provided oncologic control is not compromised, according to investigators.
Fewer Systematic Biopsy Cores May Not Lower PCa Detection Rate

In a study of patients undergoing transperineal prostate biopsy, the detection rate of clinically significant prostate cancer did not differ significantly between targeted biopsy (TB) with fewer systematic biopsy (SB) cores and TB with SB of the whole prostate.

Latest Prostate Cancer News

Metastatic Prostate Cancer in US Continues Its Upward Trend

December 3, 2021

Rising incidence rates of metastatic prostate cancer in the US coincide temporally with USPSTF recommendations against routine PSA-based prostate cancer screening.

Greater Lymph Node Dissection During Prostate Cancer Surgery Ups Survival

Jody A. Charnow

December 3, 2021

Study finds lower mortality rates associated with excisions of higher numbers of lymph nodes in patients with intermediate- and high-risk prostate cancer.

Urology consultation: MRI of a male pelvis showing the bladder and the prostate.

Risk for High-Grade Prostate Cancer Is Low Following Negative MRI, Biopsy

Jody A. Charnow

December 3, 2021

In a study, no patient was diagnosed with high-grade prostate cancer within 3 years following a negative prostate MRI and negative systematic prostate biopsy.

Taking allopurinol pills helps kidney disease

Adding Anti-Androgens to Late Salvage RT May Improve PCa Outcomes

Jody A. Charnow

December 2, 2021

Concomitant anti-androgen therapy may ameliorate the worse outcomes associated with delayed salvage radiation therapy for recurrent prostate cancer after radical surgery.

Death Rate Lower for Hispanic Men With Advanced Prostate Cancer

Jody Charnow

December 2, 2021

Among men with Medicare coverage, Hispanic men had a significant 37% decreased risk for death compared with both non-Hispanic White men and Black men, a study found.