Bladder wall thickness and the pattern of uroflowmetry curve shape are associated with the healing period in pediatric patients with overactive bladder (OAB), according to researchers.

The finding is from a retrospective study of 117 children with OAB aged 5 to 15 years who, at initial presentation, underwent abdominal ultrasound examinations and uroflowmetry and initiation of behavior modifications such as timed voiding, and constipation therapy.

The average healing period was 11.9 months. The investigators observed no significant difference in health period based on age, percentage of urination frequency, nocturnal enuresis, and constipation. The healing period was significantly shorter in the group with a bladder wall thickness of 5 mm or more compared with patients whose bladder wall thickness is less than 5 mm, Masaki Fuyama, MD, and colleagues from Showa University in Yokohama, Kanagawa, Japan, reported in Pediatrics International.

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In addition, patients with a tower-shaped curve on uroflowmetry had a significantly shorter healing period than those with a bell-shaped curve, according to the investigators.


Fuyama M, Ikeda H, Oyake C, et al. Clinical features and association of bladder ultrasound findings and uroflowmetry with healing period of overactive bladder in children. Pediatr Int. 2018;