Patients with type 2 diabetes are at significantly higher risk for overactive bladder (OAB) symptoms than nondiabetics, according to researchers.

In addition, among type 2 diabetics, higher glycosylated hemoglobin (HbA1c) levels predict a significantly increased likelihood of OAB/urgency, urge incontinence, and nocturia.

Hann-Chorng Kuo, MD, of Buddhist Tzu Chi General Hospital Hualien, Taiwan, and colleagues studied 279 type 2 diabetics and 578 age- and gender-matched controls without diabetes. OAB was present in 28% of the diabetics compared with only 16.3% of controls, which translated into a twofold increased risk of OAB in the diabetics, Dr. Kuo’s team report online in the International Journal of Urology. Urgency also was present in 28% and 16.3% of diabetics and controls, respectively.

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Forty-eight percent of the diabetics had nocturia compared with 39.1% of controls, which translated into a 44% increased risk of nocturia among the diabetics.

In addition, among diabetics, each one-point rise in HbA1c was associated with a significant 24%, 20%, and 17% increased risk of OAB/urgency, urge incontinence, and nocturia, respectively.