There may be a bidirectional association between depression and nocturia, according to a review published in The Journal of Urology.
Benjamin N. Breyer, M.D., from the University of California in San Francisco, and colleagues conducted a literature review to identify abstracts and original, review, and editorial articles on nocturia and mood disorders, specifically depression and anxiety.
The researchers observed a strong association between nocturia and depression/anxiety based on cross-sectional (level 3) data. A single prospective study found a unidirectional relationship with depression leading to nocturia. Nocturia posed a greater risk for depression in men than in women. The effect of serotonin reuptake inhibitors on nocturia demonstrated conflicting results.
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“Practicing clinicians should consider administering a brief self-administered scale to assess for depression in patients with nocturia,” the authors write.
Several authors disclosed financial ties to the pharmaceutical industry.
