(HealthDay News) — The majority of melanomas arise from new lesions rather than existing moles, according to a review published online in the Journal of the American Academy of Dermatology.

Researchers conducted a review of 38 previously published medical studies involving 20,126 melanomas.

The findings showed that only 29.1% of the skin cancers started in moles patients already had, while 70.9% arose as new lesions on the skin.

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“In conclusion, in this systematic review and meta-analysis we found that less than one-third of melanomas were nevus-associated and that nevus-associated melanomas were less thick than de novo melanomas,” the authors write. “Among nevus-associated melanomas, we found no significant differences in the distribution of dysplastic and nondysplastic remnants.”

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  1. Pampena R, Kyrgidis A, Lallas A, et al. A meta-analysis of nevus-associated melanoma: Prevalence and practical implications. J Am Acad Dermatol. 29 Aug 2017. doi: 10.1016/j.jaad.2017.06.149