Metabolic syndrome is associated with a significantly increased risk of kidney stones, according to a study.

The study, by researchers at Asan Medical Center in Seoul, Korea led by Hyung Keun Park, MD, PhD, examined data from 34,895 individuals who underwent general health screening between January 2006 and December 2006. Of these, 4,779 (13.7%) had metabolic syndrome and 839 (2.4%) had radiologic evidence of kidney stones.

Compared with individuals who did not have metabolic syndrome, those with the syndrome had a significant 25% increased risk of kidney stones, after adjusting for confounding variables, the investigators reported online (ahead of print) in the American Journal of Kidney Diseases. In addition, the study showed that hypertensive individuals had a 47% increased risk compared with those who did not have hypertension.

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“Our findings suggest the need for interventional studies to test the effects of preventing and treating metabolic syndrome on the risk of kidney stone development,” the authors concluded.