Cytoreductive Nephrectomy Offers a Survival Edge in mRCC
Patients receiving modern immunotherapy for metastatic renal cell carcinoma have a decreased risk of death if they also undergo cytoreductive nephrectomy, a study found.
Kidney Cancer
KIDNEY CANCER
High-Throughput Multichain Immune Repertoire Sequencing for Prediction of Treatment Response in Renal Cell Carcinoma
Next-generation sequencing is being increasingly used to characterize the diversity of T-cell and B-cell receptors in individuals.
Cancer Risk Halved With Bariatric Surgery-Linked Weight Loss
Hazard ratio 0.44 for incident cancer with loss of at least 20 to 35 versus <20% of total body weight.
High Vitamin D Binding Protein Levels Up RCC Risk
The highest vs lowest quartile of vitamin D binding protein was associated with 4.1-fold increased odds of renal cell carcinoma in adjusted analyses.
Microwave Ablation Feasible for cT1b Renal Cell Carcinoma
Microwave ablation for cT1b renal cell carcinoma has outcomes that compare favorably with partial and radical nephrectomy, a study found.
Machine-Based CT May Help Identify BAP1 Mutation Status in Clear Cell Renal Cell Carcinoma
The method could more accurately classify patients with clear cell disease.
Risk for Cancer Incidence, Mortality Increased With Psoriasis
Overall cancer incidence and mortality for kidney and other cancers up with severe psoriasis.
Longer Duration of Steroids May Affect Outcomes During Anti-PD-1 Treatment
The use of steroids for the treatment of immune-related adverse events may have survival consequences.
RCC With Isolated Lymph Node Metastases Has Poor Prognosis After Surgery
Following nephrectomy for renal cell carcinoma with lymph node involvement, patients have a 5-year survival rate of only 28%, a new study found.
Durable Positive Effects of First-Line Pembrolizumab in Advanced RCC Reported
Updated follow-up of patients in the KEYNOTE-427 trial showed that first-line pembrolizumab for advanced clear cell renal cell carcinoma exerts favorable antitumor activity after a median 23 months of follow-up.
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