Cytology and Biomarkers in NMIBC
Cystoscopy and cytology remain the standard for diagnosis, but a plethora of urinary biomarkers could someday be a useful adjunct to NMIBC surveillance.
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Bladder Cancer Linked to Stewed, Roasted Meat
High intake of stewed or roasted meat, but not boiled, fried, or preserved meat, is associated with increased odds of bladder cancer, a case-control study found.
Immunotherapy + Chemo May Improve Outcomes in Metastatic Urothelial Cancer
First-line treatment with both atezolizumab and platinum-based chemotherapy (PBC) is associated with prolonged progression-free survival vs PBC alone in patients with metastatic urothelial cancer, a study found.
NAC Increases Pathologic Complete Response Rate in High-Risk MIBC
In a study of patients with high-risk muscle-invasive bladder cancer, patients who received cisplatin-based neoadjuvant chemotherapy had a 3.6 times higher rate of pathologic complete response compared with those who had upfront radical cystectomy.
Women Have Lower Relative Survival After Bladder Cancer Diagnosis
In a study, women with bladder cancer had approximately 1.5-fold higher mortality than men — but only in the short term.
Best Practices for Handling BCG Waste
What is the proper procedure for handling bacillus Calmette-Guerin (BCG) waste? Does the room need to be closed off after instilling the drug into the bladder?
Robotic Partial Cystectomy Does Not Hike Positive Surgical Margin Risk
Investigators report finding no significant difference in positive surgical margin rates among open, laparoscopic, and robotic-assisted approaches to partial cystectomy.
Delayed RC for Histologic Variant Urothelial Bladder Cancer Ups Death Risk
Each 1-month delay in radical cystectomy following diagnosis of variant histology urothelial carcinoma of the bladder was associated with a 36% increased risk of death, a study found.
Robotic, Open Cystectomy for Bladder Cancer Offer Comparable Outcomes
In a propensity score matched analysis, robotic-assisted and open radical cystectomy for urothelial bladder cancer did not differ significantly with respect to disease recurrence and cancer-specific mortality rates.
Combo Shows Promise as Alternative for Metastatic Urothelial Carcinoma
In a phase 2 trial, a regimen of gemcitabine plus eribulin compared favorably with other regimens for the first-line treatment of cisplatin-ineligible patients with metastatic urothelial carcinoma.
UTUC With Isolated Lymph Node Involvement Predicts Poor Survival
Patients who undergo surgical resection of nonmetastatic upper tract urothelial carcinoma with isolated lymph node involvement have a 5-year overall survival rate of only 24%, a study found.
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