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Ureteroscopy Prior to UTUC Surgery Ups Intravesical Recurrence Risk

Preoperative diagnostic ureteroscopy (URS) before radical nephroureterectomy for upper tract urothelial carcinoma (UTUC) is a risk factor for intravesical recurrence, according to investigators. In a study of 453 patients with UTUC undergoing radical nephroureterectomy (RNU), a significantly higher proportion of patients who underwent preoperative URS experienced intravesical recurrence (IVR) than those who did not (43.8%…
Ongoing studies are expected to provide information about how to sequence cabozantinib in clinical p

Risk Factors for UTUC Intravesical Recurrence Identified

Tumor diameter and stage are independent risk factors for intravesical recurrence of organ-confined upper tract urothelial carcinoma (UTUC) following radical nephroureterectomy (RNU), according to a new study. In a retrospective study of patients with organ-confined UTUC who underwent RNU combined with bladder cuff resection, investigators propensity score matched 42 patients who experienced intravesical recurrence (IVR)…

Bladder Cancer Surgery Safe Following Neoadjuvant Immunotherapy

Toxicity profile and readmission rates among patients who underwent radical cystectomy and pelvic lymph node dissection following neoadjuvant pembrolizumab are in line with previously published series reporting 90-day outcomes after RC with or without neoadjuvant chemotherapy.
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