(HealthDay News) — Poor sleep quality is associated with an increased prevalence of lower urinary tract symptoms (LUTS)/benign prostatic hyperplasia (BPH), according to a study published online in Frontiers in Aging Neuroscience.

Yifan Li, from the West China Hospital of Sichuan University in Chengdu, and colleagues evaluated the association between sleep disorders and LUTS/BPH among Chinese men. The analysis included 11,824 survey respondents.

The researchers found that when adjusting for confounding variables, the global Pittsburgh sleep quality index score (odds ratio [OR], 1.257) and its 5 components (subjective sleep quality: OR, 1.376; sleep latency: OR, 0.656; sleep duration: OR, 1.441; habitual sleep efficiency: OR, 1.369; and daytime dysfunction: OR, 1.702) were significantly positively correlated with LUTS/BPH prevalence. There were significant interaction effects seen by age subgroups, with sleep disorders more significantly associated with the risk for LUTS/BPH among older participants.


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“Our findings suggested that sleep disorders are associated with an increased prevalence of LUTS/BPH. Moreover, the significant interaction between age and sleep disorders showed that older people are more likely to develop LUTS/BPH due to sleep disorders,” the authors write. “Our study provides data support for the possible future proposal to prevent LUTS/BPH by improving sleep disorders. Their potential biological mechanisms need to be further studied.”

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